iPTMnet Report for Q4G163 (FBXO43)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q4G163 / FBX43_HUMAN
Protein Name F-box only protein 43
Gene Name Name: FBXO43
Synonyms:EMI2;
Organism Homo sapiens (Human)

PRO ID PR:Q4G163
DAG View
PRO Name F-box only protein 43 (human)
Definition An F-box only protein 43 that is encoded in the genome of human.
Short Label hFBXO43
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q4G163 (FBXO43) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T18 Phosphorylation PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus   UniProt 15753281
S121 Phosphorylation PhosphoSitePlus
T138 O-Glycosylation GlyGen 29237092
S198 Phosphorylation PhosphoSitePlus
T234 Phosphorylation PhosphoSitePlus   UniProt 16407128
T234 Phosphorylation Q9UQM7 (CAMK2A) PhosphoSitePlus 16407128
S334 Phosphorylation PhosphoSitePlus   UniProt 15753281
S349 Phosphorylation PhosphoSitePlus
T499 Phosphorylation PhosphoSitePlus
Y503 Phosphorylation PhosphoSitePlus
K507 Ubiquitination PhosphoSitePlus
T551 Phosphorylation PhosphoSitePlus
T607 Phosphorylation PhosphoSitePlus
S618 Phosphorylation PhosphoSitePlus
S619 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T18 S18 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S53 F53 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S121 F121 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ]
T138 A138 Biomuta DOID:1319 / brain cancer [ cosmic ]
S198 F198 Biomuta DOID:4159 / skin cancer [ cosmic ]
T234 K234 Biomuta DOID:1324 / lung cancer [ cosmic ]