iPTMnet Report for Q4G0N4 (NADK2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q4G0N4 / NAKD2_HUMAN
Protein Name NAD kinase 2, mitochondrial precursor
Gene Name Name: NADK2
Synonyms:C5orf33,MNADK,NADKD1;
Organism Homo sapiens (Human)

PRO ID PR:Q4G0N4
DAG View
PRO Name NAD kinase 2, mitochondrial (human)
Definition An NAD kinase 2, mitochondrial that is encoded in the genome of human.
Short Label hNADK2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q4G0N4 (NADK2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K76 Acetylation PhosphoSitePlus
S93 Phosphorylation PhosphoSitePlus
K98 Acetylation PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
T183 Phosphorylation PhosphoSitePlus
S188 Phosphorylation PhosphoSitePlus   UniProt 24275569
S289 Phosphorylation PhosphoSitePlus
S294 Phosphorylation PhosphoSitePlus
K304 Acetylation PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
K339 Acetylation PhosphoSitePlus
K339 Ubiquitination PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus
K355 Ubiquitination PhosphoSitePlus
T357 Phosphorylation PhosphoSitePlus
S363 Phosphorylation PhosphoSitePlus
S367 Phosphorylation PhosphoSitePlus   UniProt 24275569
K372 Ubiquitination PhosphoSitePlus
S376 Phosphorylation PhosphoSitePlus
R384 Methylation PhosphoSitePlus
C393 S-Nitrosylation dbSNO 19483679
K397 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T183 Phosphorylation HPRD 20166139
S188 Phosphorylation HPRD 20166139
Site PTM Type PTM Enzyme Score Source PMID
T20 Phosphorylation HPRD 20166139
S25 Phosphorylation HPRD 20166139


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S25 F25 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S93 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S188 F188 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S294 L294 Biomuta DOID:4159 / skin cancer [ cosmic ]