iPTMnet Report for Q4ADV7 (RIC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q4ADV7 / RIC1_HUMAN
Protein Name Guanine nucleotide exchange factor subunit RIC1
Gene Name Name: RIC1
Synonyms:CIP150;
Organism Homo sapiens (Human)

PRO ID PR:Q4ADV7
DAG View
PRO Name guanine nucleotide exchange factor subunit RIC1 (human)
Definition A guanine nucleotide exchange factor subunit RIC1 that is encoded in the genome of human.
Short Label hRIC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q4ADV7 (RIC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K9 Ubiquitination PhosphoSitePlus
Y105 Phosphorylation PhosphoSitePlus
K111 Ubiquitination PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
C255 Methylation IEDB 31844290
Y277 Phosphorylation PhosphoSitePlus
K396 Ubiquitination PhosphoSitePlus
K453 Ubiquitination PhosphoSitePlus
K458 Ubiquitination PhosphoSitePlus
S459 Phosphorylation PhosphoSitePlus
S632 Phosphorylation PhosphoSitePlus
T658 Phosphorylation PhosphoSitePlus
K759 Ubiquitination PhosphoSitePlus
Y777 Phosphorylation PhosphoSitePlus
S990 Phosphorylation PhosphoSitePlus
T992 Phosphorylation PhosphoSitePlus   UniProt 23186163
S995 Phosphorylation PhosphoSitePlus
T996 Phosphorylation PhosphoSitePlus   UniProt 18669648
S1004 Phosphorylation PhosphoSitePlus
S1015 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1017 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1019 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1021 Phosphorylation PhosphoSitePlus
K1029 Ubiquitination PhosphoSitePlus
K1034 Ubiquitination PhosphoSitePlus
S1037 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y1058 Phosphorylation PhosphoSitePlus
K1112 Ubiquitination PhosphoSitePlus
K1148 Methylation PhosphoSitePlus
S1151 Phosphorylation PhosphoSitePlus
S1170 Phosphorylation PhosphoSitePlus
S1172 Phosphorylation PhosphoSitePlus
T1366 Phosphorylation PhosphoSitePlus
S1380 Phosphorylation PhosphoSitePlus
S1393 Phosphorylation PhosphoSitePlus
S1394 Phosphorylation PhosphoSitePlus
S1398 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y105 H105 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1004 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S1017 R1017 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1398 I1398 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]