iPTMnet Report for Q49AR2 (C5orf22)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q49AR2 / CE022_HUMAN
Protein Name UPF0489 protein C5orf22
Gene Name Name: C5orf22
Organism Homo sapiens (Human)

PRO ID PR:Q49AR2
DAG View
PRO Name UPF0489 protein C5orf22 (human)
Definition A UPF0489 protein C5orf22 that is encoded in the genome of human.
Short Label hC5orf22
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q49AR2 (C5orf22) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T73 Phosphorylation PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
K150 Sumoylation PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
S192 Phosphorylation PhosphoSitePlus
C195 S-Nitrosylation dbSNO 26338901
S197 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K204 Ubiquitination PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S197 Phosphorylation HPRD 19413330, 18669648
Site PTM Type PTM Enzyme Score Source PMID
K46 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T73 A73 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K150 Q150 Biomuta DOID:363 / uterine cancer [ icgc ]
S197 A197 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]