iPTMnet Report for Q49A26 (GLYR1)
Protein Information
| UniProt AC / UniProt ID | Q49A26 / GLYR1_HUMAN |
| Protein Name | Cytokine-like nuclear factor N-PAC |
| Gene Name | Name: GLYR1 Synonyms:HIBDL,NDF; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q49A26 |
| PRO Name | cytokine-like nuclear factor N-PAC (human) |
| Definition | A nuclear protein NP60 that is encoded in the genome of human. |
| Short Label | hGLYR1 |
| Category | organism-gene |
Q49A26 (GLYR1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K25 | Acetylation | score1 | PhosphoSitePlus | |||
| K61 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y63 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K72 | Acetylation | score1 | PhosphoSitePlus | |||
| K77 | Acetylation | score1 | PhosphoSitePlus | |||
| R91 | Methylation | score1 | PhosphoSitePlus | |||
| K96 | Methylation | score1 | PhosphoSitePlus | |||
| K108 | Methylation | score1 | PhosphoSitePlus | |||
| S113 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S114 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S118 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S122 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S130 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 20068231 | ||
| S132 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K135 | Acetylation | score1 | PhosphoSitePlus | |||
| S148 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S149 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S151 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S152 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S158 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S167 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 17081983 | ||
| K201 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K211 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K227 | Acetylation | score1 | PhosphoSitePlus | |||
| K227 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C231 | Methylation | score1 | IEDB | 31844290 | ||
| Y232 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K237 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T257 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K269 | Sumoylation | score1 | PhosphoSitePlus | |||
| S280 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T292 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T294 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K302 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K335 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K338 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S345 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C486 | Methylation | score1 | IEDB | 31844290 | ||
| K495 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K505 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K532 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K535 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S540 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 23186163, 20068231 | ||
| S545 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S114 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S130 | Phosphorylation | score0 | HPRD | 17081983, 19691289, 18452278, ... | ||
| S132 | Phosphorylation | score0 | HPRD | 18669648, 17081983 | ||
| S151 | Phosphorylation | score0 | HPRD | 17081983 | ||
| S167 | Phosphorylation | score0 | HPRD | 19651622, 17081983, 20068231 | ||
| S187 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S540 | Phosphorylation | score0 | HPRD | 19691289, 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S114 | N114 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S130 | N130 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S151 | C151 | Biomuta | DOID:4362 / cervical cancer [ icgc ] | |
| S158 | Y158 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| T294 | A294 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K338 | N338 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| C486 | G486 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K495 | Q495 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |
DAG View