iPTMnet Report Q495A1 TIGIT

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q495A1 / TIGIT_HUMAN
Protein Name	T-cell immunoreceptor with Ig and ITIM domains precursor
Gene Name	Name: TIGIT Synonyms:VSIG9,VSTM3;
Organism	Homo sapiens (Human)

PRO ID	PR:Q495A1 DAG View
PRO Name	T-cell immunoreceptor with Ig and ITIM domains (human)
Definition	A T cell immunoreceptor with Ig and ITIM domains that is encoded in the genome of human.
Short Label	hTIGIT
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q495A1 (TIGIT) as Substrate

Q495A1

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T149	Phosphorylation		score1	PhosphoSitePlus
	T155	Phosphorylation		score1	PhosphoSitePlus
	T164	Phosphorylation		score1	PhosphoSitePlus
	S174	Phosphorylation		score1	PhosphoSitePlus
	Y225	Phosphorylation		score3	PhosphoSitePlus RLIMS-P	23154388

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
T164	P164	Biomuta		DOID:363 / uterine cancer [ cosmic, icgc ]