iPTMnet Report for Q460N5 (PARP14)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q460N5 / PAR14_HUMAN
Protein Name Protein mono-ADP-ribosyltransferase PARP14
Gene Name Name: PARP14
Synonyms:BAL2;
Organism Homo sapiens (Human)

PRO ID PR:Q460N5
DAG View
PRO Name protein mono-ADP-ribosyltransferase PARP14 (human)
Definition A protein mono-ADP-ribosyltransferase PARP14 that is encoded in the genome of human.
Short Label hPARP14
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q460N5 (PARP14) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K26 Ubiquitination PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus   UniProt 23186163
K35 Ubiquitination PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
K80 Ubiquitination PhosphoSitePlus
T92 Phosphorylation PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
Y242 Phosphorylation PhosphoSitePlus
S243 Phosphorylation PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
Y300 Phosphorylation PhosphoSitePlus
Y301 Phosphorylation PhosphoSitePlus
Y309 Phosphorylation PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
S325 Phosphorylation PhosphoSitePlus
K332 Ubiquitination PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
K381 Ubiquitination PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
S393 Phosphorylation PhosphoSitePlus
K399 Methylation PhosphoSitePlus
K399 Ubiquitination PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
K414 Ubiquitination PhosphoSitePlus
S444 Phosphorylation PhosphoSitePlus
K459 Ubiquitination PhosphoSitePlus
K461 Ubiquitination PhosphoSitePlus
K470 Ubiquitination PhosphoSitePlus
C494 Methylation IEDB 31844290
K511 Ubiquitination PhosphoSitePlus
K519 Ubiquitination PhosphoSitePlus
K527 Ubiquitination PhosphoSitePlus
K556 Ubiquitination PhosphoSitePlus
C557 Methylation IEDB 31844290
K599 Ubiquitination PhosphoSitePlus
K606 Ubiquitination PhosphoSitePlus
K615 Ubiquitination PhosphoSitePlus
K623 Ubiquitination PhosphoSitePlus
K670 Ubiquitination PhosphoSitePlus
K678 Ubiquitination PhosphoSitePlus
T688 Phosphorylation PhosphoSitePlus
K711 Ubiquitination PhosphoSitePlus
K713 Ubiquitination PhosphoSitePlus
K721 Ubiquitination PhosphoSitePlus
K726 Ubiquitination PhosphoSitePlus
K732 Ubiquitination PhosphoSitePlus
K741 Ubiquitination PhosphoSitePlus
K747 Ubiquitination PhosphoSitePlus
K751 Ubiquitination PhosphoSitePlus
K757 Ubiquitination PhosphoSitePlus
K782 Ubiquitination PhosphoSitePlus
K791 Ubiquitination PhosphoSitePlus
S823 Phosphorylation PhosphoSitePlus
K828 Ubiquitination PhosphoSitePlus
K839 Ubiquitination PhosphoSitePlus
K854 Ubiquitination PhosphoSitePlus
K868 Ubiquitination PhosphoSitePlus
K871 Ubiquitination PhosphoSitePlus
S886 Phosphorylation PhosphoSitePlus
C893 Methylation IEDB 31844290
K949 Ubiquitination PhosphoSitePlus
K955 Ubiquitination PhosphoSitePlus
K965 Ubiquitination PhosphoSitePlus
K975 Ubiquitination PhosphoSitePlus
K979 Ubiquitination PhosphoSitePlus
K1000 Ubiquitination PhosphoSitePlus
K1005 Ubiquitination PhosphoSitePlus
S1007 Phosphorylation PhosphoSitePlus
S1010 Phosphorylation PhosphoSitePlus
K1020 Ubiquitination PhosphoSitePlus
K1027 Ubiquitination PhosphoSitePlus
K1048 Ubiquitination PhosphoSitePlus
C1086 Methylation IEDB 31844290
S1104 O-Glycosylation GlyGen 30379171, 28411811, 36240223
C1115 Methylation IEDB 31844290
K1158 Ubiquitination PhosphoSitePlus
K1162 Ubiquitination PhosphoSitePlus
K1198 Acetylation PhosphoSitePlus
K1198 Ubiquitination PhosphoSitePlus
K1201 Acetylation PhosphoSitePlus
K1203 Ubiquitination PhosphoSitePlus
S1247 Phosphorylation PhosphoSitePlus
T1248 Phosphorylation PhosphoSitePlus
S1251 Phosphorylation PhosphoSitePlus
K1260 Ubiquitination PhosphoSitePlus
K1282 Acetylation PhosphoSitePlus
K1282 Ubiquitination PhosphoSitePlus
K1296 Acetylation PhosphoSitePlus
K1296 Ubiquitination PhosphoSitePlus
K1308 Acetylation PhosphoSitePlus
K1308 Ubiquitination PhosphoSitePlus
K1320 Ubiquitination PhosphoSitePlus
K1321 Ubiquitination PhosphoSitePlus
K1337 Ubiquitination PhosphoSitePlus
K1357 Ubiquitination PhosphoSitePlus
K1385 Ubiquitination PhosphoSitePlus
S1396 Phosphorylation PhosphoSitePlus
K1400 Ubiquitination PhosphoSitePlus
S1403 Phosphorylation PhosphoSitePlus   UniProt 24275569
K1409 Ubiquitination PhosphoSitePlus
S1411 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1415 Ubiquitination PhosphoSitePlus
K1422 Ubiquitination PhosphoSitePlus
K1465 Ubiquitination PhosphoSitePlus
K1470 Ubiquitination PhosphoSitePlus
K1480 Ubiquitination PhosphoSitePlus
K1481 Ubiquitination PhosphoSitePlus
K1491 Ubiquitination PhosphoSitePlus
K1496 Ubiquitination PhosphoSitePlus
K1516 Ubiquitination PhosphoSitePlus
K1555 Ubiquitination PhosphoSitePlus
K1570 Ubiquitination PhosphoSitePlus
Y1576 Phosphorylation PhosphoSitePlus
Y1583 Phosphorylation PhosphoSitePlus
K1589 Ubiquitination PhosphoSitePlus
S1592 Phosphorylation PhosphoSitePlus
K1602 Ubiquitination PhosphoSitePlus
K1613 Ubiquitination PhosphoSitePlus
K1635 Ubiquitination PhosphoSitePlus
K1663 Ubiquitination PhosphoSitePlus
K1670 Acetylation PhosphoSitePlus
K1670 Ubiquitination PhosphoSitePlus
K1678 Ubiquitination PhosphoSitePlus
Y1701 Phosphorylation PhosphoSitePlus
K1704 Ubiquitination PhosphoSitePlus
K1736 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S33 N33 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S33 G33 Biomuta DOID:363 / uterine cancer [ icgc ]
K287 R287 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K287 Q287 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K317 E317 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K332 E332 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K337 N337 Biomuta DOID:363 / uterine cancer [ icgc ]
K381 N381 Biomuta DOID:363 / uterine cancer [ icgc ]
S444 N444 Biomuta [ cosmic ]
K459 T459 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K461 R461 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K741 E741 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K757 N757 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1104 L1104 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S1104 P1104 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K1158 N1158 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ icgc ]
S1247 L1247 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1247 * Biomuta DOID:4362 / cervical cancer [ cosmic ]
S1251 L1251 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K1321 T1321 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
K1337 E1337 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1403 A1403 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1411 C1411 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K1415 N1415 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K1422 R1422 Biomuta DOID:2021 / placenta cancer [ cosmic ]
K1470 N1470 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1470 R1470 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K1491 N1491 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K1516 N1516 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
Y1576 H1576 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K1589 N1589 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K1663 N1663 Biomuta DOID:9256 / colorectal cancer [ cosmic ]