iPTMnet Report for Q3YEC7 (RABL6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q3YEC7 / RABL6_HUMAN
Protein Name Rab-like protein 6
Gene Name Name: RABL6
Synonyms:C9orf86,PARF;
Organism Homo sapiens (Human)

PRO ID PR:Q3YEC7
DAG View
PRO Name Rab-like protein 6 (human)
Definition A Rab-like protein 6 that is encoded in the genome of human.
Short Label hRABL6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q3YEC7 (RABL6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S11 Phosphorylation PhosphoSitePlus
K19 Ubiquitination PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus
Y42 Phosphorylation PhosphoSitePlus
T54 Phosphorylation PhosphoSitePlus
S356 Phosphorylation PhosphoSitePlus
S359 Phosphorylation PhosphoSitePlus
S402 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
T407 Phosphorylation PhosphoSitePlus
T408 Phosphorylation PhosphoSitePlus
S425 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 20068231, ...19690332
S427 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 20068231
S454 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S464 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
T468 Phosphorylation PhosphoSitePlus
S470 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S471 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S492 Phosphorylation PhosphoSitePlus   UniProt 23186163
T496 Phosphorylation PhosphoSitePlus
S504 Phosphorylation PhosphoSitePlus
R508 Methylation PhosphoSitePlus
T510 Phosphorylation PhosphoSitePlus
T513 Phosphorylation PhosphoSitePlus
R514 Methylation PhosphoSitePlus
T515 O-Glycosylation GlyGen 31373491
S525 O-Glycosylation GlyGen 23301498, 31373491
S525 Phosphorylation PhosphoSitePlus   UniProt 23186163
T528 Phosphorylation PhosphoSitePlus
S535 Phosphorylation PhosphoSitePlus
S551 Phosphorylation phospho.ELM 17081983
S552 Phosphorylation phospho.ELM 17081983
S553 Phosphorylation phospho.ELM 17081983
S555 Phosphorylation phospho.ELM 17081983
S577 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983
S580 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S596 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...24275569, 20068231
T599 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...24275569, 20068231
S625 Phosphorylation PhosphoSitePlus
S640 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
S641 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
K662 Acetylation PhosphoSitePlus
T702 Phosphorylation PhosphoSitePlus
Y726 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S356 Phosphorylation HPRD 20068231
S402 Phosphorylation HPRD 19651622, 20068231
T408 Phosphorylation HPRD 19664994
S425 Phosphorylation HPRD 19651622, 17081983, 20068231
S427 Phosphorylation HPRD 19651622, 20068231
S454 Phosphorylation HPRD 19651622, 20058876, 17081983
S464 Phosphorylation HPRD 19651622, 17081983
T468 Phosphorylation HPRD 19651622
S470 Phosphorylation HPRD 19413330, 19651622, 17081983
S471 Phosphorylation HPRD 19413330, 19651622, 17081983
S492 Phosphorylation HPRD 19413330
T496 Phosphorylation HPRD 19413330
S596 Phosphorylation HPRD 19651622, 20058876, 20068231, ...20230923
T599 Phosphorylation HPRD 19651622, 20058876, 20068231, ...20230923
S640 Phosphorylation HPRD 19413330, 19651622, 20068231
S641 Phosphorylation HPRD 19413330, 19651622, 20068231
Y726 Phosphorylation HPRD 19901323, 17389395
Site PTM Type PTM Enzyme Score Source PMID
S217 Phosphorylation PhosphoSitePlus
Y222 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T54 M54 Biomuta DOID:1319 / brain cancer [ icgc ]
S356 I356 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S454 N454 Biomuta DOID:4159 / skin cancer [ cosmic ]
S470 W470 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S470 L470 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S504 L504 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, tcga ]
T510 A510 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R514 K514 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T528 I528 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S535 G535 Biomuta [ cosmic ]
S551 F551 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S552 L552 Biomuta DOID:1319 / brain cancer [ cosmic ]
S641 T641 Biomuta DOID:2174 / ocular cancer [ tcga ]
K662 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]