iPTMnet Report for Q3YBM2 (TMEM176B)
Protein Information
| UniProt AC / UniProt ID | Q3YBM2 / T176B_HUMAN |
| Protein Name | Transmembrane protein 176B |
| Gene Name | Name: TMEM176B Synonyms:LR8; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q3YBM2 |
| PRO Name | transmembrane protein 176B (human) |
| Definition | A transmembrane protein 176B that is encoded in the genome of human. |
| Short Label | hTMEM176B |
| Category | organism-gene |
DAG ViewQ3YBM2 (TMEM176B) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S42 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S236 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S245 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S254 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S258 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S254 | L254 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S258 | L258 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |
