iPTMnet Report for Q3V6T2 (CCDC88A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q3V6T2 / GRDN_HUMAN
Protein Name Girdin
Gene Name Name: CCDC88A
Synonyms:APE;
Organism Homo sapiens (Human)

PRO ID PR:Q3V6T2
DAG View
PRO Name girdin (human)
Definition A girdin that is encoded in the genome of human.
Short Label hCCDC88A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q3V6T2 (CCDC88A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S233 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 23186163, 29538402
S237 Phosphorylation PhosphoSitePlus   RLIMS-P 29538402
S245 Phosphorylation PhosphoSitePlus   RLIMS-P 27813479
K448 Ubiquitination PhosphoSitePlus
S449 Phosphorylation PhosphoSitePlus   UniProt 23186163
K464 Ubiquitination PhosphoSitePlus
K498 Ubiquitination PhosphoSitePlus
S528 Phosphorylation PhosphoSitePlus
S595 Phosphorylation PhosphoSitePlus
S600 Phosphorylation PhosphoSitePlus
S697 Phosphorylation PhosphoSitePlus
S712 Phosphorylation PhosphoSitePlus
K714 Ubiquitination PhosphoSitePlus
S747 Phosphorylation PhosphoSitePlus
T771 Phosphorylation PhosphoSitePlus
S775 Phosphorylation PhosphoSitePlus
S825 O-Glycosylation GlyGen 30379171
Y876 Phosphorylation PhosphoSitePlus
S879 Phosphorylation IEDB 35494241
S913 Phosphorylation PhosphoSitePlus
K939 Ubiquitination PhosphoSitePlus
K955 Ubiquitination PhosphoSitePlus
S959 Phosphorylation PhosphoSitePlus
T999 Phosphorylation PhosphoSitePlus
S1020 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1162 Ubiquitination PhosphoSitePlus
K1207 Ubiquitination PhosphoSitePlus
K1220 Acetylation PhosphoSitePlus
K1225 Acetylation PhosphoSitePlus
K1259 Ubiquitination PhosphoSitePlus
S1273 Phosphorylation PhosphoSitePlus
S1278 Phosphorylation PhosphoSitePlus
K1291 Ubiquitination PhosphoSitePlus
K1305 Ubiquitination PhosphoSitePlus
C1310 Methylation IEDB 31844290
K1376 Ubiquitination PhosphoSitePlus
Y1381 Phosphorylation PhosphoSitePlus
Y1384 Phosphorylation PhosphoSitePlus
S1387 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 16964243
T1397 Phosphorylation PhosphoSitePlus
K1416 Ubiquitination PhosphoSitePlus
S1417 Phosphorylation P31749 (AKT1) neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 23186163, 33717652, 16139227
T1419 Phosphorylation PhosphoSitePlus
T1421 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1439 Phosphorylation PhosphoSitePlus
K1459 Ubiquitination PhosphoSitePlus
S1461 Phosphorylation PhosphoSitePlus
S1462 Phosphorylation PhosphoSitePlus
K1467 Methylation PhosphoSitePlus
S1498 Phosphorylation PhosphoSitePlus
T1541 Phosphorylation IEDB 32387766
K1551 Ubiquitination PhosphoSitePlus
T1560 Phosphorylation PhosphoSitePlus
S1561 Phosphorylation PhosphoSitePlus
S1566 Phosphorylation PhosphoSitePlus
S1583 Phosphorylation PhosphoSitePlus
S1587 Phosphorylation PhosphoSitePlus
S1590 Phosphorylation PhosphoSitePlus
S1603 Phosphorylation PhosphoSitePlus
K1608 Ubiquitination PhosphoSitePlus
S1652 Phosphorylation PhosphoSitePlus
S1653 Phosphorylation PhosphoSitePlus
S1661 Phosphorylation PhosphoSitePlus
T1673 Phosphorylation PhosphoSitePlus   UniProt 18669648
S1675 Phosphorylation Q00535 (CDK5) PhosphoSitePlus   UniProt 26286990, 27621449
S1678 Phosphorylation PhosphoSitePlus
S1690 Phosphorylation Q04759 (PRKCQ) PhosphoSitePlus   UniProt 23509302, 27621449
S1700 Phosphorylation PhosphoSitePlus
S1702 Phosphorylation PhosphoSitePlus
S1715 Phosphorylation PhosphoSitePlus
S1717 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1723 Ubiquitination PhosphoSitePlus
S1734 Phosphorylation PhosphoSitePlus
S1736 Phosphorylation PhosphoSitePlus
Y1744 Phosphorylation PhosphoSitePlus
K1750 Ubiquitination PhosphoSitePlus
K1760 Ubiquitination PhosphoSitePlus
T1761 Phosphorylation PhosphoSitePlus
T1764 Phosphorylation PhosphoSitePlus
Y1765 Phosphorylation PhosphoSitePlus   UniProt 21954290
K1772 Ubiquitination PhosphoSitePlus
T1777 Phosphorylation PhosphoSitePlus
K1785 Ubiquitination PhosphoSitePlus
S1787 Phosphorylation PhosphoSitePlus
S1788 Phosphorylation PhosphoSitePlus
S1790 Phosphorylation PhosphoSitePlus
K1794 Methylation PhosphoSitePlus
S1796 Phosphorylation PhosphoSitePlus
Y1799 Phosphorylation P12931 (SRC) PhosphoSitePlus   UniProt 21954290, 25707853
T1801 Phosphorylation PhosphoSitePlus
S1807 Phosphorylation PhosphoSitePlus
T1819 O-Glycosylation GlyGen 30379171
T1819 Phosphorylation PhosphoSitePlus
S1820 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1834 Phosphorylation PhosphoSitePlus
S1837 Phosphorylation PhosphoSitePlus   UniProt 18669648
S1844 Phosphorylation PhosphoSitePlus
T1847 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S1278 Phosphorylation HPRD 18767875
S1387 Phosphorylation HPRD 18669648, 19664994, 16964243
S1417 Phosphorylation P31749 (AKT1) HPRD 16139227, 20068231
T1419 Phosphorylation HPRD 20068231
T1645 Phosphorylation HPRD 18669648, 20068231
S1647 Phosphorylation HPRD 18669648, 15345747
S1650 Phosphorylation HPRD 18669648
S1674 Phosphorylation HPRD 19651622, 15345747, 19664994, ...20058876
S1689 Phosphorylation Q04759 (PRKCQ) HPRD   neXtProt 23509302, 19664994
Y1737 Phosphorylation HPRD 19901323
T1773 Phosphorylation HPRD 18212344
T1791 Phosphorylation HPRD 20068231
S1792 Phosphorylation HPRD 20068231
S1809 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S712 Y712 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S747 Y747 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S747 F747 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y876 H876 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S959 * Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
S1278 F1278 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1387 C1387 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K1459 N1459 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K1459 Q1459 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S1583 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S1674 I1674 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1702 I1702 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1760 N1760 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S1787 F1787 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1787 Y1787 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1796 C1796 Biomuta DOID:1612 / breast cancer [ cosmic ]