iPTMnet Report for Q3U182 (Crtc2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q3U182 / CRTC2_MOUSE
Protein Name CREB-regulated transcription coactivator 2
Gene Name Name: Crtc2
Synonyms:Torc2;
Organism Mus musculus (Mouse)

PRO ID PR:Q3U182
DAG View
PRO Name CREB-regulated transcription coactivator 2 (mouse)
Definition A CREB-regulated transcription coactivator 2 that is encoded in the genome of mouse.
Short Label mCRTC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q3U182 (Crtc2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S15 Phosphorylation RLIMS-P 30337688
T37 O-Glycosylation GlyGen   PhosphoSitePlus 18323454
R51 Methylation UniProt 24570487
S64 Phosphorylation PhosphoSitePlus
S70 O-Glycosylation GlyGen   PhosphoSitePlus 18323454
S70 Phosphorylation PhosphoSitePlus   UniProt 21183079, 28235073
S86 Phosphorylation PhosphoSitePlus
S90 Phosphorylation PhosphoSitePlus
R99 Methylation UniProt 24570487
R120 Methylation UniProt 24570487
Y121 Phosphorylation PhosphoSitePlus
R123 Methylation UniProt 24570487
S127 O-Glycosylation GlyGen   PhosphoSitePlus 18323454
S127 Phosphorylation PhosphoSitePlus
S128 O-Glycosylation GlyGen   PhosphoSitePlus 18323454
Y130 Phosphorylation PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus   RLIMS-P 33434948, 30232001
S141 Phosphorylation PhosphoSitePlus
R161 Methylation PhosphoSitePlus   UniProt 24129315, 24570487
S164 Phosphorylation PhosphoSitePlus
R168 Methylation UniProt 24570487
T169 Phosphorylation PhosphoSitePlus   UniProt 28235073
S171 O-Glycosylation GlyGen   PhosphoSitePlus 18323454
S171 Phosphorylation PRO   PhosphoSitePlus   RLIMS-P   UniProt 29211348, 20551288, 16684769, ...25088745, 16308421, 17805301, 30611118, 16148943, 21183079, 28235073
S171 Phosphorylation Q8CFH6 (Sik2) PhosphoSitePlus 17805301
S173 O-Glycosylation GlyGen   PhosphoSitePlus 18323454
S173 Phosphorylation PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus
T187 Phosphorylation PhosphoSitePlus
K229 Acetylation PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 20551288, 30611118
S307 Phosphorylation PhosphoSitePlus   RLIMS-P 20551288
T308 Phosphorylation RLIMS-P 27239959
T309 Phosphorylation RLIMS-P 28589878
S358 Phosphorylation RLIMS-P 17805301
S369 Phosphorylation PhosphoSitePlus
S394 Phosphorylation PhosphoSitePlus
S434 Phosphorylation PhosphoSitePlus   UniProt 21183079
S437 Phosphorylation PhosphoSitePlus
S457 Phosphorylation PhosphoSitePlus
T459 Phosphorylation PhosphoSitePlus
T463 Phosphorylation PhosphoSitePlus
Y489 Phosphorylation PhosphoSitePlus
S490 Phosphorylation PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus
T502 Phosphorylation PhosphoSitePlus
S612 Phosphorylation PhosphoSitePlus   UniProt 17242355, 21183079
S622 Phosphorylation PhosphoSitePlus   UniProt 21183079
S623 Phosphorylation PhosphoSitePlus   UniProt 21183079
S627 Phosphorylation PhosphoSitePlus
K628 Acetylation PhosphoSitePlus
K628 Ubiquitination PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000045523 (mCRTC2/Phos:1) pS171 PRO 16684769


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P31749 (AKT1) T450 Q3U182 (Crtc2) inhibited_association eFIP 30428057
Phosphorylation P42345 (MTOR) S2481 Q3U182 (Crtc2) unknown eFIP 24479521
Phosphorylation Q6R327 (RICTOR) T1135 Q3U182 (Crtc2) unknown eFIP 32642408
Phosphorylation Q9BPZ7 (MAPKAP1) T398 Q3U182 (Crtc2) unknown eFIP 31798957
Phosphorylation Q9BPZ7 (MAPKAP1) T398 Q3U182 (Crtc2) unknown eFIP 24481632