iPTMnet Report for Q3SY84 (KRT71)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q3SY84 / K2C71_HUMAN
Protein Name Keratin, type II cytoskeletal 71
Gene Name Name: KRT71
Synonyms:K6IRS1,KB34,KRT6IRS1;
Organism Homo sapiens (Human)

PRO ID PR:Q3SY84
DAG View
PRO Name keratin, type II cytoskeletal 71 (human)
Definition A keratin, type II cytoskeletal 71 that is encoded in the genome of human.
Short Label hKRT71
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q3SY84 (KRT71) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus
S21 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
S36 Phosphorylation PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
Y69 Phosphorylation PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
K147 Acetylation PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
Y220 Phosphorylation PhosphoSitePlus
T228 Phosphorylation PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus
Y323 Phosphorylation PhosphoSitePlus
T325 Phosphorylation PhosphoSitePlus
S360 Phosphorylation PhosphoSitePlus
S370 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y415 Phosphorylation PhosphoSitePlus
S420 Phosphorylation PhosphoSitePlus
T431 Phosphorylation PhosphoSitePlus
K510 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S9 L9 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S40 R40 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S45 N45 Biomuta DOID:3571 / liver cancer [ cosmic ]
S50 R50 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y323 C323 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S370 F370 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S420 N420 Biomuta DOID:10534 / stomach cancer [ cosmic ]