Protein Information

Cytoscape View


UniProt AC / UniProt ID Q3SY69 / AL1L2_HUMAN
Protein Name Mitochondrial 10-formyltetrahydrofolate dehydrogenase
Gene Name Name: ALDH1L2
Organism Homo sapiens (Human)

PRO ID PR:Q3SY69
DAG View
PRO Name mitochondrial 10-formyltetrahydrofolate dehydrogenase (human)
Definition A mitochondrial 10-formyltetrahydrofolate dehydrogenase that is encoded in the genome of human.
Short Label hALDH1L2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q3SY69 (ALDH1L2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K57 Acetylation PhosphoSitePlus
K77 Acetylation PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
T109 Phosphorylation PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
Y127 Phosphorylation PhosphoSitePlus
T270 Phosphorylation PhosphoSitePlus
T338 Phosphorylation PhosphoSitePlus
S371 Phosphorylation PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus
T550 Phosphorylation PhosphoSitePlus
T670 Phosphorylation PhosphoSitePlus
C728 Methylation IEDB 31844290
K754 Acetylation PhosphoSitePlus
K886 Acetylation PhosphoSitePlus
K903 Acetylation PhosphoSitePlus   UniProt 19608861


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S124 C124 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]