iPTMnet Report for Q3MIT2 (PUS10)
Protein Information
| UniProt AC / UniProt ID | Q3MIT2 / PUS10_HUMAN |
| Protein Name | tRNA pseudouridine synthase Pus10 |
| Gene Name | Name: PUS10 Synonyms:CCDC139; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q3MIT2 |
| PRO Name | tRNA pseudouridine synthase Pus10 (human) |
| Definition | A tRNA pseudouridine synthase Pus10 that is encoded in the genome of human. |
| Short Label | hPUS10 |
| Category | organism-gene |
DAG ViewQ3MIT2 (PUS10) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| C21 | Methylation | score1 | IEDB | 31844290 | ||
| S79 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 17525332 | ||
| S84 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 17525332, 23186163, 18077418 | ||
| T99 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S153 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S171 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| S173 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| K183 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K427 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K436 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S153 | F153 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| K427 | N427 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
