iPTMnet Report for Q3MII6 (TBC1D25)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q3MII6 / TBC25_HUMAN
Protein Name TBC1 domain family member 25
Gene Name Name: TBC1D25
Synonyms:OATL1;
Organism Homo sapiens (Human)

PRO ID PR:Q3MII6
DAG View
PRO Name TBC1 domain family member 25 (human)
Definition A TBC1 domain family member 25 that is encoded in the genome of human.
Short Label hTBC1D25
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q3MII6 (TBC1D25) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T3 Phosphorylation PhosphoSitePlus
S5 Phosphorylation PhosphoSitePlus
S8 Phosphorylation PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
T159 Phosphorylation phospho.ELM 18669648
T160 O-Glycosylation GlyGen 30379171, 28657654
T166 Phosphorylation phospho.ELM 18669648
S262 O-Glycosylation GlyGen 30379171, 28657654
K269 Ubiquitination PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
K376 Ubiquitination PhosphoSitePlus
T480 Phosphorylation PhosphoSitePlus
S506 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...24275569
S540 Phosphorylation PhosphoSitePlus
S559 Phosphorylation PhosphoSitePlus
S564 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T159 Phosphorylation HPRD 18669648, 20068231
T166 Phosphorylation HPRD 18669648
S506 Phosphorylation HPRD 20058876, 18767875, 19664994, ...19651622, 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T159 M159 Biomuta DOID:1319 / brain cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
T166 I166 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K269 N269 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S506 I506 Biomuta DOID:4159 / skin cancer [ cosmic ]
S540 Y540 Biomuta DOID:363 / uterine cancer [ icgc ]