iPTMnet Report for Q3KP66 (INAVA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q3KP66 / INAVA_HUMAN
Protein Name Innate immunity activator protein
Gene Name Name: INAVA
Synonyms:C1orf106;
Organism Homo sapiens (Human)

PRO ID PR:Q3KP66
DAG View
PRO Name innate immunity activator protein (human)
Definition An innate immunity activator protein that is encoded in the genome of human.
Short Label hINAVA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q3KP66 (INAVA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R49 Methylation PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
T95 Phosphorylation PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus
T116 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
S246 Phosphorylation PhosphoSitePlus
S313 Phosphorylation PhosphoSitePlus
Y333 Phosphorylation PhosphoSitePlus
S369 Phosphorylation PhosphoSitePlus
Y370 Phosphorylation PhosphoSitePlus
S387 Phosphorylation PhosphoSitePlus
T391 Phosphorylation PhosphoSitePlus
R398 Methylation PhosphoSitePlus
R405 Methylation PhosphoSitePlus
S408 Phosphorylation PhosphoSitePlus
R492 Methylation PhosphoSitePlus
Y516 Phosphorylation PhosphoSitePlus
Y546 Phosphorylation PhosphoSitePlus
T551 Phosphorylation PhosphoSitePlus
R554 Methylation PhosphoSitePlus
Y555 Phosphorylation PhosphoSitePlus
S563 Phosphorylation PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus
R578 Methylation PhosphoSitePlus
S581 O-Glycosylation GlyGen 30379171
R595 Methylation PhosphoSitePlus
S605 Phosphorylation PhosphoSitePlus
S616 Phosphorylation PhosphoSitePlus
R626 Methylation PhosphoSitePlus
R631 Methylation PhosphoSitePlus
S643 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y333 F333 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
R405 M405 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic ]
S408 Y408 Biomuta DOID:4159 / skin cancer [ cosmic ]
S408 F408 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R492 C492 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
Y546 H546 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R554 C554 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
S643 L643 Biomuta DOID:9256 / colorectal cancer [ cosmic ]