Protein Information

Cytoscape View


UniProt AC / UniProt ID Q3B7T1 / EDRF1_HUMAN
Protein Name Erythroid differentiation-related factor 1
Gene Name Name: EDRF1
Synonyms:C10orf137;
Organism Homo sapiens (Human)

PRO ID PR:Q3B7T1
DAG View
PRO Name erythroid differentiation-related factor 1 (human)
Definition An erythroid differentiation-related factor 1 that is encoded in the genome of human.
Short Label hEDRF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q3B7T1 (EDRF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S30 Phosphorylation PhosphoSitePlus
K99 Acetylation PhosphoSitePlus
K102 Acetylation PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
K188 Acetylation PhosphoSitePlus
K192 Acetylation PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
K397 Ubiquitination PhosphoSitePlus
Y448 Phosphorylation PhosphoSitePlus
T453 Phosphorylation PhosphoSitePlus
K578 Ubiquitination PhosphoSitePlus
S631 Phosphorylation PhosphoSitePlus
K637 Ubiquitination PhosphoSitePlus
R644 Methylation PhosphoSitePlus
K652 Ubiquitination PhosphoSitePlus
K666 Ubiquitination PhosphoSitePlus
K691 Ubiquitination PhosphoSitePlus
K694 Ubiquitination PhosphoSitePlus
K774 Ubiquitination PhosphoSitePlus
K826 Ubiquitination PhosphoSitePlus
K877 Ubiquitination PhosphoSitePlus
K925 Ubiquitination PhosphoSitePlus
K938 Ubiquitination PhosphoSitePlus
Y1006 Phosphorylation PhosphoSitePlus
S1011 Phosphorylation PhosphoSitePlus
S1013 Phosphorylation PhosphoSitePlus
Y1021 Phosphorylation PhosphoSitePlus
S1144 Phosphorylation PhosphoSitePlus
S1146 Phosphorylation PhosphoSitePlus
K1192 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K301 N301 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K877 E877 Biomuta DOID:9256 / colorectal cancer [ tcga ]
K925 Q925 Biomuta DOID:363 / uterine cancer [ tcga ]
S1011 L1011 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S1144 F1144 Biomuta DOID:363 / uterine cancer [ tcga ]