iPTMnet Report for Q32P44 (EML3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q32P44 / EMAL3_HUMAN
Protein Name Echinoderm microtubule-associated protein-like 3
Gene Name Name: EML3
Organism Homo sapiens (Human)

PRO ID PR:Q32P44
DAG View
PRO Name echinoderm microtubule-associated protein-like 3 (human)
Definition An echinoderm microtubule-associated protein-like 3 that is encoded in the genome of human.
Short Label hEML3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q32P44 (EML3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
R13 Methylation PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus
S156 Phosphorylation PhosphoSitePlus
S161 Phosphorylation PhosphoSitePlus
K173 Acetylation PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
S176 Phosphorylation O14757 (CHEK1) phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...18669648, 21851590, 19690332, 20068231
S177 Phosphorylation PhosphoSitePlus
R190 Methylation PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
S197 Phosphorylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus   UniProt 23186163
S204 Phosphorylation PhosphoSitePlus   UniProt 23186163
S207 Phosphorylation PhosphoSitePlus
T445 O-Glycosylation GlyGen 29351928
T445 Phosphorylation PhosphoSitePlus
T447 Phosphorylation PhosphoSitePlus
Y456 Phosphorylation PhosphoSitePlus
S490 Phosphorylation PhosphoSitePlus
S492 Phosphorylation PhosphoSitePlus
T494 Phosphorylation PhosphoSitePlus
T575 O-Glycosylation GlyGen 29351928
K577 Ubiquitination PhosphoSitePlus
C816 Methylation IEDB 31844290
K817 Ubiquitination PhosphoSitePlus
C825 Methylation IEDB 31844290
S840 Phosphorylation PhosphoSitePlus
T843 Phosphorylation PhosphoSitePlus
S844 Phosphorylation PhosphoSitePlus
T881 O-Glycosylation GlyGen 29351928
T881 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   UniProt 16964243, 18220336, 18847512, ...30723163, 18669648
S883 O-Glycosylation GlyGen 29351928
S883 Phosphorylation P24941 (CDK2) PhosphoSitePlus   UniProt 18847512, 23186163, 24275569
T885 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S887 Phosphorylation PhosphoSitePlus
S889 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S892 Phosphorylation PhosphoSitePlus
S893 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S176 Phosphorylation HPRD 16964243, 18767875, 19651622, ...18669648, 20166139, 20068231, 18212344
S177 Phosphorylation HPRD 20068231
S198 Phosphorylation HPRD 19691289
S207 Phosphorylation HPRD 19691289
S490 Phosphorylation HPRD 20068231
S492 Phosphorylation HPRD 20068231
T494 Phosphorylation HPRD 20068231
T881 Phosphorylation HPRD 18669648, 16964243, 20068231, ...19691289
T885 Phosphorylation HPRD 18669648
S889 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S900 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R13 Q13 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S129 N129 Biomuta DOID:4159 / skin cancer [ cosmic ]
S156 C156 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S177 F177 Biomuta DOID:4159 / skin cancer [ cosmic ]
R190 H190 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R190 C190 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S197 C197 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S204 Y204 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T445 I445 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S490 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K577 N577 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S844 N844 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T881 K881 Biomuta DOID:3571 / liver cancer [ cosmic ]