iPTMnet Report for Q32NC0 (C18orf21)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q32NC0 / CR021_HUMAN
Protein Name UPF0711 protein C18orf21
Gene Name Name: C18orf21
Synonyms:XTP13;ORFNames:PNAS-124,PNAS-131;
Organism Homo sapiens (Human)

PRO ID PR:Q32NC0
DAG View
PRO Name UPF0711 protein C18orf21 (human)
Definition A UPF0711 protein C18orf21 that is encoded in the genome of human.
Short Label hC18orf21
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q32NC0 (C18orf21) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y6 Phosphorylation PhosphoSitePlus
S117 Phosphorylation PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
S126 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16964243
T130 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16964243
T132 Phosphorylation phospho.ELM 18669648
K134 Ubiquitination PhosphoSitePlus
T139 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S152 Phosphorylation PhosphoSitePlus
S158 Phosphorylation PhosphoSitePlus
T165 Phosphorylation PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
S195 Phosphorylation PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus
S213 Phosphorylation PhosphoSitePlus
K215 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y6 Phosphorylation HPRD 20068231
T110 Phosphorylation HPRD 20068231
S117 Phosphorylation HPRD 17924679
S122 Phosphorylation HPRD 17924679
S126 Phosphorylation HPRD 18669648, 16964243, 20068231
T130 Phosphorylation HPRD 18669648, 16964243, 20068231
T132 Phosphorylation HPRD 18669648
T139 Phosphorylation HPRD 18669648, 19691289
S152 Phosphorylation HPRD 20068231
S158 Phosphorylation HPRD 18691976, 19007248
S161 Phosphorylation HPRD 19007248
S168 Phosphorylation HPRD 19691289
S212 Phosphorylation HPRD 20068231
S213 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S117 I117 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S126 N126 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T132 A132 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:2531 / hematologic cancer [ icgc ] DOID:11054 / urinary bladder cancer [ cosmic ]
S158 R158 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S158 N158 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S195 I195 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S213 P213 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]