iPTMnet Report for Q2VPK5 (CTU2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q2VPK5 / CTU2_HUMAN
Protein Name Cytoplasmic tRNA 2-thiolation protein 2
Gene Name Name: CTU2
Synonyms:C16orf84,NCS2;
Organism Homo sapiens (Human)

PRO ID PR:Q2VPK5
DAG View
PRO Name cytoplasmic tRNA 2-thiolation protein 2 (human)
Definition A cytoplasmic tRNA 2-thiolation protein 2 that is encoded in the genome of human.
Short Label hCTU2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q2VPK5 (CTU2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C2 Acetylation UniProt 19413330
K238 Ubiquitination PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
K373 Ubiquitination PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus   UniProt 20068231
S419 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
T428 Phosphorylation PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus   UniProt 23186163
K471 Ubiquitination PhosphoSitePlus
S508 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
S515 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S415 Phosphorylation HPRD 20068231
S419 Phosphorylation HPRD 19413330, 19651622, 18669648
S508 Phosphorylation HPRD 18767875, 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S415 Phosphorylation HPRD 20068231
S419 Phosphorylation HPRD 19413330, 19651622, 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K261 N261 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K313 E313 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K313 T313 Biomuta DOID:3571 / liver cancer [ cosmic ]
S435 A435 Biomuta DOID:3571 / liver cancer [ cosmic ]
K471 N471 Biomuta DOID:363 / uterine cancer [ icgc ]