iPTMnet Report for Q2VIQ3 (KIF4B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q2VIQ3 / KIF4B_HUMAN
Protein Name Chromosome-associated kinesin KIF4B
Gene Name Name: KIF4B
Organism Homo sapiens (Human)

PRO ID PR:Q2VIQ3
DAG View
PRO Name chromosome-associated kinesin KIF4B (human)
Definition A chromosome-associated kinesin KIF4B that is encoded in the genome of human.
Short Label hKIF4B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q2VIQ3 (KIF4B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K129 Ubiquitination PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
S197 Phosphorylation PhosphoSitePlus
T199 Phosphorylation PhosphoSitePlus
T203 Phosphorylation PhosphoSitePlus
S207 Phosphorylation PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
S210 Phosphorylation PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
K251 Ubiquitination PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
S394 Phosphorylation HPRD   PhosphoSitePlus 19691289
K401 Sumoylation PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
S407 Phosphorylation PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
K460 Sumoylation PhosphoSitePlus
Y557 Phosphorylation PhosphoSitePlus
K624 Acetylation PhosphoSitePlus
K670 Ubiquitination PhosphoSitePlus
K676 Ubiquitination PhosphoSitePlus
Y684 Phosphorylation PhosphoSitePlus
K688 Ubiquitination PhosphoSitePlus
K715 Ubiquitination PhosphoSitePlus
K840 Ubiquitination PhosphoSitePlus
K868 Acetylation PhosphoSitePlus
Y869 Phosphorylation PhosphoSitePlus
S876 Phosphorylation PhosphoSitePlus
S877 Phosphorylation PhosphoSitePlus
S961 Phosphorylation PhosphoSitePlus
S1038 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 19691289, 18220336
K1097 Ubiquitination PhosphoSitePlus
S1106 Phosphorylation PhosphoSitePlus
S1113 Phosphorylation PhosphoSitePlus
T1117 Phosphorylation PhosphoSitePlus
T1135 Phosphorylation PhosphoSitePlus
S1138 Phosphorylation PhosphoSitePlus
S1141 Phosphorylation PhosphoSitePlus
T1148 Phosphorylation PhosphoSitePlus
T1151 Phosphorylation PhosphoSitePlus
T1163 Phosphorylation PhosphoSitePlus
S1166 Phosphorylation PhosphoSitePlus
T1183 Phosphorylation PhosphoSitePlus
T1200 Phosphorylation PhosphoSitePlus
Y1202 Phosphorylation PhosphoSitePlus
S1218 Phosphorylation PhosphoSitePlus
S1221 Phosphorylation PhosphoSitePlus
S1224 Phosphorylation PhosphoSitePlus
S1227 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S207 F207 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S209 L209 Biomuta DOID:1319 / brain cancer [ icgc ]
S210 F210 Biomuta DOID:4159 / skin cancer [ cosmic ]
S234 Y234 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K258 R258 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S394 Y394 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K401 T401 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S407 C407 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K715 N715 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
S876 F876 Biomuta DOID:4159 / skin cancer [ cosmic ]
S877 F877 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1097 N1097 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1113 C1113 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ] DOID:11934 / head and neck cancer [ icgc ]
T1117 R1117 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1135 N1135 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S1138 F1138 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1141 F1141 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T1151 I1151 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1163 I1163 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1166 N1166 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1200 I1200 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1224 C1224 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]