iPTMnet Report for Q2TB90 (HKDC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q2TB90 / HKDC1_HUMAN
Protein Name Hexokinase HKDC1
Gene Name Name: HKDC1
Organism Homo sapiens (Human)

PRO ID PR:Q2TB90
DAG View
PRO Name hexokinase HKDC1 (human)
Definition A hexokinase HKDC1 that is encoded in the genome of human.
Short Label hHKDC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q2TB90 (HKDC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K15 Acetylation PhosphoSitePlus
S32 Phosphorylation PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
K173 Acetylation PhosphoSitePlus
K174 Acetylation PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
T330 Phosphorylation PhosphoSitePlus
K333 Acetylation PhosphoSitePlus
Y417 Phosphorylation PhosphoSitePlus
K418 Ubiquitination PhosphoSitePlus
K500 Ubiquitination PhosphoSitePlus
K502 Ubiquitination PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus
T508 Phosphorylation PhosphoSitePlus
T514 Phosphorylation PhosphoSitePlus
K527 Acetylation PhosphoSitePlus
K544 Acetylation PhosphoSitePlus
S609 Phosphorylation PhosphoSitePlus
K737 Ubiquitination PhosphoSitePlus
Y748 Phosphorylation PhosphoSitePlus
S772 Phosphorylation PhosphoSitePlus
S791 Phosphorylation PhosphoSitePlus
T877 Phosphorylation PhosphoSitePlus
S892 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y748 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S32 F32 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S155 Y155 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S155 C155 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K544 M544 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y748 S748 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S791 N791 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]