iPTMnet Report for Q2TAY7 (SMU1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q2TAY7 / SMU1_HUMAN
Protein Name WD40 repeat-containing protein SMU1
Gene Name Name: SMU1
Organism Homo sapiens (Human)

PRO ID PR:Q2TAY7
DAG View
PRO Name WD40 repeat-containing protein SMU1 (human)
Definition A WD40 repeat-containing protein SMU1 that is encoded in the genome of human.
Short Label hSMU1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q2TAY7 (SMU1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S2 Acetylation UniProt 19413330, 22814378, 22223895
Y17 Phosphorylation PhosphoSitePlus
K19 Ubiquitination PhosphoSitePlus
S22 Phosphorylation IEDB   PhosphoSitePlus 27920218
K107 Ubiquitination PhosphoSitePlus
Y114 Phosphorylation PhosphoSitePlus
R123 Methylation PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
K210 Acetylation PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
C219 Methylation IEDB 31844290
C269 Methylation IEDB 31844290
K287 Ubiquitination PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
K308 Ubiquitination PhosphoSitePlus
C312 Methylation IEDB 31844290
S324 Phosphorylation PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
K343 Ubiquitination PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
C383 Methylation IEDB 31844290
S434 Phosphorylation PhosphoSitePlus
S436 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y114 Phosphorylation HPRD 15570572
S215 Phosphorylation HPRD 20068231
T245 Phosphorylation HPRD 20068231
T311 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R123 S123 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K200 T200 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S215 * Biomuta DOID:2394 / ovarian cancer [ cosmic ]
K292 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S324 N324 Biomuta DOID:363 / uterine cancer [ icgc ]
S434 I434 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]