iPTMnet Report for Q2TAC2 (CCDC57)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q2TAC2 / CCD57_HUMAN
Protein Name Coiled-coil domain-containing protein 57
Gene Name Name: CCDC57
Organism Homo sapiens (Human)

PRO ID PR:Q2TAC2
DAG View
PRO Name coiled-coil domain-containing protein 57 (human)
Definition A coiled-coil domain-containing protein 57 that is encoded in the genome of human.
Short Label hCCDC57
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q2TAC2 (CCDC57) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation PhosphoSitePlus
S227 O-Glycosylation GlyGen 30379171, 29351928
R274 Methylation PhosphoSitePlus
T315 Phosphorylation PhosphoSitePlus
S445 Phosphorylation PhosphoSitePlus
S453 Phosphorylation PhosphoSitePlus
S457 Phosphorylation PhosphoSitePlus
T622 Phosphorylation PhosphoSitePlus
T626 O-Glycosylation GlyGen 30379171, 29351928
S639 O-Glycosylation GlyGen 30379171, 29351928
S639 Phosphorylation PhosphoSitePlus
S648 Phosphorylation PhosphoSitePlus
S655 Phosphorylation PhosphoSitePlus
K750 Acetylation PhosphoSitePlus
T889 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R274 M274 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T315 A315 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S453 N453 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S648 F648 Biomuta DOID:4159 / skin cancer [ cosmic ]