iPTMnet Report for Q2QGD7 (ZXDC)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q2QGD7 / ZXDC_HUMAN
Protein Name Zinc finger protein ZXDC
Gene Name Name: ZXDC
Synonyms:ZXDL;
Organism Homo sapiens (Human)

PRO ID PR:Q2QGD7
DAG View
PRO Name zinc finger protein ZXDC (human)
Definition A zinc finger protein ZXDC that is encoded in the genome of human.
Short Label hZXDC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q2QGD7 (ZXDC) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R13 Methylation PhosphoSitePlus
R25 Methylation PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus   UniProt 23186163
S171 Phosphorylation PhosphoSitePlus
T172 Phosphorylation PhosphoSitePlus   UniProt 23186163
K247 Ubiquitination PhosphoSitePlus
T250 Phosphorylation PhosphoSitePlus
T251 Phosphorylation PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
K269 Sumoylation PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
K397 Ubiquitination PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
K440 Ubiquitination PhosphoSitePlus
K441 Ubiquitination PhosphoSitePlus
K450 Ubiquitination PhosphoSitePlus
K465 Sumoylation PhosphoSitePlus
K465 Ubiquitination PhosphoSitePlus
S523 Phosphorylation PhosphoSitePlus
T628 Phosphorylation PhosphoSitePlus
T639 Phosphorylation PhosphoSitePlus
S651 Phosphorylation PhosphoSitePlus
K660 Sumoylation PhosphoSitePlus
S665 Phosphorylation PhosphoSitePlus   UniProt 24275569
T821 Phosphorylation IEDB 35494241


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T250 S250 Biomuta DOID:184 / bone cancer [ cosmic ]
K260 M260 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K282 Q282 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K465 Q465 Biomuta DOID:1324 / lung cancer [ cosmic ]
S651 R651 Biomuta DOID:1324 / lung cancer [ cosmic ]
S651 N651 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]