iPTMnet Report for Q2M3G4 (SHROOM1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q2M3G4 / SHRM1_HUMAN
Protein Name Protein Shroom1
Gene Name Name: SHROOM1
Synonyms:APXL2,KIAA1960;
Organism Homo sapiens (Human)

PRO ID PR:Q2M3G4
DAG View
PRO Name protein Shroom1 (human)
Definition A protein Shroom1 that is encoded in the genome of human.
Short Label hSHROOM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q2M3G4 (SHROOM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S12 Phosphorylation PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus   UniProt 23186163
S26 Phosphorylation PhosphoSitePlus
Y33 Phosphorylation PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus
S49 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y62 Phosphorylation PhosphoSitePlus
T98 Phosphorylation PhosphoSitePlus
T103 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 24275569, 18220336
T112 Phosphorylation PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus   UniProt 24275569
S137 Phosphorylation PhosphoSitePlus   UniProt 24275569
S157 Phosphorylation IEDB 27920218
R164 Methylation PhosphoSitePlus
S166 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S186 Phosphorylation PhosphoSitePlus
S188 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S190 Phosphorylation PhosphoSitePlus   UniProt 23186163
R202 Methylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus   UniProt 23186163
K228 Ubiquitination PhosphoSitePlus
R234 Methylation PhosphoSitePlus
R240 Methylation PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus
S302 Phosphorylation PhosphoSitePlus
S304 Phosphorylation PhosphoSitePlus
S306 Phosphorylation PhosphoSitePlus
S308 Phosphorylation PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
S401 Phosphorylation PhosphoSitePlus
T515 Phosphorylation PhosphoSitePlus
K651 Ubiquitination PhosphoSitePlus
S735 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S735 Phosphorylation PhosphoSitePlus
S737 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T103 I103 Biomuta DOID:11054 / urinary bladder cancer [ icgc ]
S224 * Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
R234 W234 Biomuta DOID:4159 / skin cancer [ cosmic ]
R240 Q240 Biomuta DOID:363 / uterine cancer [ icgc ]
S306 R306 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S308 L308 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S401 * Biomuta DOID:4159 / skin cancer [ cosmic ]