iPTMnet Report for Q2M389 (WASHC4)
Protein Information
| UniProt AC / UniProt ID | Q2M389 / WASC4_HUMAN |
| Protein Name | WASH complex subunit 4 |
| Gene Name | Name: WASHC4 Synonyms:KIAA1033; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q2M389 |
| PRO Name | WASH complex subunit 4 (human) |
| Definition | A WASH complex subunit 4 that is encoded in the genome of human. |
| Short Label | hWASHC4 |
| Category | organism-gene |
Q2M389 (WASHC4) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 20068231 | ||
| S7 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
| S19 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K21 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K29 | Methylation | score1 | PhosphoSitePlus | |||
| K29 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K33 | Methylation | score1 | PhosphoSitePlus | |||
| K33 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y38 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K81 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K103 | Acetylation | score1 | PhosphoSitePlus | |||
| Y119 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y155 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y169 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K221 | Acetylation | score1 | IEDB | 34357683 | ||
| K225 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K233 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K240 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K302 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K373 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K378 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K384 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K394 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y405 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y406 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K422 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y461 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K474 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C477 | Methylation | score1 | IEDB | 31844290 | ||
| Y491 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S494 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S500 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K553 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K573 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K585 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K701 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K813 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K877 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K883 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S937 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K968 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K1089 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S1097 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1101 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T1109 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1111 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T1154 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T1156 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1157 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1162 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S7 | Phosphorylation | score0 | HPRD | 18691976, 20068231 | ||
| S1157 | Phosphorylation | score0 | HPRD | 18452278 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S826 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S7 | Y7 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| K29 | N29 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| Y38 | H38 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| Y119 | C119 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K373 | T373 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| Y406 | D406 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| Y461 | F461 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K585 | E585 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| K701 | T701 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K968 | R968 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
DAG View