iPTMnet Report for Q27J81 (INF2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q27J81 / INF2_HUMAN
Protein Name Inverted formin-2
Gene Name Name: INF2
Synonyms:C14orf151,C14orf173;
Organism Homo sapiens (Human)

PRO ID PR:Q27J81
DAG View
PRO Name inverted formin-2 (human)
Definition An inverted formin-2 that is encoded in the genome of human.
Short Label hINF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q27J81 (INF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22814378
K4 Methylation PhosphoSitePlus
K4 Ubiquitination PhosphoSitePlus
K15 Ubiquitination PhosphoSitePlus
K17 Ubiquitination PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
T26 Phosphorylation PhosphoSitePlus
S93 Phosphorylation PhosphoSitePlus
T100 Phosphorylation PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
T134 Phosphorylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus   UniProt 23186163
K355 Ubiquitination PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus
S359 Phosphorylation PhosphoSitePlus
S367 Phosphorylation PhosphoSitePlus
S371 O-Glycosylation GlyGen 23301498, 34725712, 33465208, ...28510447
S371 Phosphorylation PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus
T376 Phosphorylation PhosphoSitePlus
T378 Phosphorylation PhosphoSitePlus
T420 Phosphorylation PhosphoSitePlus
S433 Phosphorylation PhosphoSitePlus
S527 Phosphorylation PhosphoSitePlus
T561 Phosphorylation PhosphoSitePlus
K565 Ubiquitination PhosphoSitePlus
K566 Ubiquitination PhosphoSitePlus
K571 Ubiquitination PhosphoSitePlus
S574 Phosphorylation O14757 (CHEK1) PhosphoSitePlus 21851590
S589 Phosphorylation PhosphoSitePlus
S607 Phosphorylation PhosphoSitePlus
K612 Ubiquitination PhosphoSitePlus
K614 Ubiquitination PhosphoSitePlus
T617 Phosphorylation PhosphoSitePlus
K636 Ubiquitination PhosphoSitePlus
K666 Acetylation PhosphoSitePlus
K666 Ubiquitination PhosphoSitePlus
K673 Ubiquitination PhosphoSitePlus
K682 Ubiquitination PhosphoSitePlus
K792 Ubiquitination PhosphoSitePlus
K810 Ubiquitination PhosphoSitePlus
S811 Phosphorylation PhosphoSitePlus
K846 Ubiquitination PhosphoSitePlus
T850 Phosphorylation PhosphoSitePlus
K853 Ubiquitination PhosphoSitePlus
Y865 Phosphorylation PhosphoSitePlus
T866 Phosphorylation PhosphoSitePlus
K889 Ubiquitination PhosphoSitePlus
K962 Acetylation PhosphoSitePlus
K966 Acetylation PhosphoSitePlus
K966 Ubiquitination PhosphoSitePlus
R993 Methylation PhosphoSitePlus
S1000 Phosphorylation PhosphoSitePlus
S1026 O-Glycosylation GlyGen 31373491
T1054 Phosphorylation PhosphoSitePlus
S1076 Phosphorylation PhosphoSitePlus
S1077 Phosphorylation PhosphoSitePlus
Y1079 Phosphorylation PhosphoSitePlus
S1083 Phosphorylation PhosphoSitePlus
K1115 Methylation PhosphoSitePlus
S1126 Phosphorylation PhosphoSitePlus
K1132 Ubiquitination PhosphoSitePlus
S1136 Phosphorylation PhosphoSitePlus
S1147 Phosphorylation PhosphoSitePlus   UniProt 18669648
T1148 Phosphorylation PhosphoSitePlus
S1149 Phosphorylation PhosphoSitePlus   UniProt 18669648
S1158 Phosphorylation PhosphoSitePlus
T1179 Phosphorylation PhosphoSitePlus   UniProt 20068231, 24275569, 18318008
S1183 Phosphorylation PhosphoSitePlus
T1187 Phosphorylation PhosphoSitePlus
S1188 Phosphorylation PhosphoSitePlus
S1192 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S1194 Phosphorylation PhosphoSitePlus   UniProt 23186163
T1199 Phosphorylation PhosphoSitePlus
S1201 Phosphorylation PhosphoSitePlus
S1202 Phosphorylation PhosphoSitePlus
S1204 Phosphorylation PhosphoSitePlus
T1206 Phosphorylation PhosphoSitePlus   UniProt 19690332
S1227 Phosphorylation PhosphoSitePlus
S1229 Phosphorylation PhosphoSitePlus   UniProt 17081983
S1237 Phosphorylation PhosphoSitePlus
T1242 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T134 Phosphorylation HPRD 20068231
S135 Phosphorylation HPRD 20068231
T420 Phosphorylation HPRD 20068231
S586 Phosphorylation HPRD 20068231
S588 Phosphorylation HPRD 18669648
S589 Phosphorylation HPRD 18669648, 20068231
T850 Phosphorylation HPRD 20068231
S1147 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
T1148 Phosphorylation HPRD 18669648, 17081983
S1149 Phosphorylation HPRD 19651622, 18669648, 17081983
S1158 Phosphorylation HPRD 18669648
T1179 Phosphorylation HPRD 19651622, 20166139, 17081983, ...20068231, 18452278
S1183 Phosphorylation HPRD 19651622, 20068231
T1187 Phosphorylation HPRD 18510355, 19651622
S1188 Phosphorylation HPRD 19651622, 20068231, 18452278
S1192 Phosphorylation HPRD 19651622, 19691289, 20068231
S1194 Phosphorylation HPRD 17081983
T1199 Phosphorylation HPRD 17081983
S1201 Phosphorylation HPRD 17081983
S1202 Phosphorylation HPRD 17081983
S1204 Phosphorylation HPRD 18452278, 19691289, 17081983
T1206 Phosphorylation HPRD 17081983, 18452278
Site PTM Type PTM Enzyme Score Source PMID
T134 Phosphorylation HPRD 20068231
S135 Phosphorylation HPRD 20068231
T420 Phosphorylation HPRD 20068231
S586 Phosphorylation HPRD 20068231
S588 Phosphorylation HPRD 18669648
S589 Phosphorylation HPRD 18669648, 20068231
T850 Phosphorylation HPRD 20068231
S1147 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
T1148 Phosphorylation HPRD 18669648, 17081983
S1149 Phosphorylation HPRD 19651622, 18669648, 17081983
S1158 Phosphorylation HPRD 18669648
T1179 Phosphorylation HPRD 19651622, 20166139, 17081983, ...20068231, 18452278
S1183 Phosphorylation HPRD 19651622, 20068231
T1187 Phosphorylation HPRD 18510355, 19651622
S1188 Phosphorylation HPRD 19651622, 20068231, 18452278
S1192 Phosphorylation HPRD 19651622, 19691289, 20068231
S1194 Phosphorylation HPRD 17081983
T1199 Phosphorylation HPRD 17081983
S1201 Phosphorylation HPRD 17081983
S1202 Phosphorylation HPRD 17081983
S1204 Phosphorylation HPRD 18452278, 19691289, 17081983
T1206 Phosphorylation HPRD 17081983, 18452278
S1229 Phosphorylation HPRD   PhosphoSitePlus 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S23 L23 Biomuta DOID:4159 / skin cancer [ cosmic ]
T561 P561 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S574 F574 Biomuta DOID:4159 / skin cancer [ cosmic ]
S607 F607 Biomuta DOID:4159 / skin cancer [ icgc ]
K966 N966 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
R993 C993 Biomuta DOID:184 / bone cancer [ cosmic ] [ cosmic, cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:1115 / sarcoma [ icgc ]
S1136 Y1136 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1136 F1136 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1147 N1147 Biomuta DOID:184 / bone cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
T1179 M1179 Biomuta [ cosmic ] DOID:363 / uterine cancer [ icgc ] DOID:1115 / sarcoma [ icgc ]
T1179 R1179 Biomuta [ cosmic ]
S1237 F1237 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]