iPTMnet Report for Q1KMD3 (HNRNPUL2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q1KMD3 / HNRL2_HUMAN
Protein Name Heterogeneous nuclear ribonucleoprotein U-like protein 2
Gene Name Name: HNRNPUL2
Synonyms:HNRPUL2;
Organism Homo sapiens (Human)

PRO ID PR:Q1KMD3
DAG View
PRO Name heterogeneous nuclear ribonucleoprotein U-like protein 2 (human)
Definition A heterogeneous nuclear ribonucleoprotein U-like protein 2 that is encoded in the genome of human.
Short Label hHNRNPUL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q1KMD3 (HNRNPUL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K4 Acetylation PhosphoSitePlus
K7 Acetylation PhosphoSitePlus
R23 Methylation PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
C57 S-Nitrosylation dbSNO 26338901
K58 Acetylation PhosphoSitePlus
S67 Phosphorylation phospho.ELM 15302935
S138 Phosphorylation HPRD   PhosphoSitePlus 19413330
R160 Methylation PhosphoSitePlus
S161 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 18510355, 16964243, ...18691976, 20058876, 15302935, 19007248, 18452278, 19651622, 19664994, 18669648, 18707149, 20166139, 18212344, 20068231, 17081983
T165 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648, 15302935, ...20068231
S168 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648
K174 Ubiquitination PhosphoSitePlus
S185 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 15302935, 20068231
K187 Ubiquitination PhosphoSitePlus
S188 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S193 Phosphorylation PhosphoSitePlus
Y214 Phosphorylation PhosphoSitePlus
Y222 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
S226 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18691976, 18452278, 19651622, ...18669648, 20068231
S228 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 18691976, 17081983, ...18452278, 19651622, 18669648, 18510355, 20068231
T244 Phosphorylation PhosphoSitePlus
T250 Phosphorylation HPRD   PhosphoSitePlus 18452278
T252 Phosphorylation PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
S271 Phosphorylation PhosphoSitePlus
K273 Acetylation PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
T299 O-Glycosylation GlyGen 23301498, 33214551, 30379171, ...34725712, 29351928, 23576270, 34019948, 28510447, 33465208
K305 Acetylation PhosphoSitePlus
K305 Ubiquitination PhosphoSitePlus
C308 Methylation IEDB 31844290
S312 O-Glycosylation GlyGen 33465208
S319 O-Glycosylation GlyGen 23301498, 33214551, 30379171, ...34725712, 29351928, 23576270, 34019948, 28510447, 33465208
S323 O-Glycosylation GlyGen 23301498, 33214551, 30379171, ...34725712, 29351928, 23576270, 34019948, 28510447, 33465208
K342 Sumoylation PhosphoSitePlus
C363 Methylation IEDB 31844290
R397 Methylation PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
T442 Phosphorylation PhosphoSitePlus
K471 Acetylation PhosphoSitePlus
K471 Ubiquitination PhosphoSitePlus
Y481 Phosphorylation PhosphoSitePlus
R494 Methylation PhosphoSitePlus
K496 Ubiquitination PhosphoSitePlus
K506 Ubiquitination PhosphoSitePlus
S516 Phosphorylation PhosphoSitePlus
C518 Methylation IEDB 31844290
K521 Ubiquitination PhosphoSitePlus
C538 S-Nitrosylation dbSNO 26338901
S543 Phosphorylation PhosphoSitePlus
K548 Ubiquitination PhosphoSitePlus
K553 Acetylation PhosphoSitePlus
K553 Ubiquitination PhosphoSitePlus
K558 Ubiquitination PhosphoSitePlus
K570 Acetylation PhosphoSitePlus
K570 Ubiquitination PhosphoSitePlus
K571 Acetylation PhosphoSitePlus
S597 Phosphorylation PhosphoSitePlus
K601 Ubiquitination PhosphoSitePlus
Y604 Phosphorylation PhosphoSitePlus
Y610 Phosphorylation PhosphoSitePlus
K624 Sumoylation PhosphoSitePlus
K624 Ubiquitination PhosphoSitePlus
Y625 Phosphorylation PhosphoSitePlus
K631 Ubiquitination PhosphoSitePlus
S636 Phosphorylation PhosphoSitePlus
K638 Ubiquitination PhosphoSitePlus
S655 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
R656 Methylation PhosphoSitePlus
R665 Methylation PhosphoSitePlus
R666 Methylation PhosphoSitePlus
R671 Methylation PhosphoSitePlus
R684 Methylation PhosphoSitePlus
R688 Methylation PhosphoSitePlus
R693 Methylation PhosphoSitePlus
R695 Methylation PhosphoSitePlus
Y698 Phosphorylation PhosphoSitePlus
R700 Methylation PhosphoSitePlus
R704 Methylation PhosphoSitePlus
Y706 Phosphorylation PhosphoSitePlus
R712 Methylation PhosphoSitePlus
R716 Methylation PhosphoSitePlus
R720 Methylation PhosphoSitePlus
Y725 Phosphorylation PhosphoSitePlus
Y726 Phosphorylation PhosphoSitePlus
Y727 Phosphorylation PhosphoSitePlus
R735 Methylation PhosphoSitePlus
R738 Methylation PhosphoSitePlus   UniProt 24129315
Y740 Phosphorylation PhosphoSitePlus
Y741 Phosphorylation PhosphoSitePlus
Y743 Phosphorylation PhosphoSitePlus
Y746 Phosphorylation PhosphoSitePlus
R747 Methylation PhosphoSitePlus   UniProt 24129315


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C57 Y57 Biomuta DOID:11934 / head and neck cancer [ icgc ]
R160 Q160 Biomuta DOID:1324 / lung cancer [ icgc ]
S168 F168 Biomuta DOID:4159 / skin cancer [ cosmic ]
S185 R185 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S226 L226 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T250 M250 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S312 F312 Biomuta DOID:4159 / skin cancer [ cosmic ]
C363 F363 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R397 P397 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K471 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K506 E506 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S516 F516 Biomuta DOID:4159 / skin cancer [ cosmic ]
S543 F543 Biomuta DOID:5041 / esophageal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
R656 W656 Biomuta DOID:363 / uterine cancer [ icgc ]
R665 C665 Biomuta DOID:10283 / prostate cancer [ cosmic ]
R666 Q666 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R671 L671 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R671 W671 Biomuta DOID:10283 / prostate cancer [ cosmic ]
R684 T684 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R688 S688 Biomuta DOID:2021 / placenta cancer [ cosmic ]
R693 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
R700 Q700 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R700 * Biomuta DOID:4159 / skin cancer [ cosmic ]
R704 Q704 Biomuta DOID:4159 / skin cancer [ cosmic ]
R704 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
R720 W720 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R735 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R747 L747 Biomuta DOID:4159 / skin cancer [ cosmic ]
R747 W747 Biomuta DOID:9256 / colorectal cancer [ cosmic ]