Protein Information

Cytoscape View

UniProt AC / UniProt ID Q17RY0 / CPEB4_HUMAN
Protein Name Cytoplasmic polyadenylation element-binding protein 4
Gene Name Name: CPEB4
Organism Homo sapiens (Human)

DAG View
PRO Name cytoplasmic polyadenylation element-binding protein 4 (human)
Definition A cytoplasmic polyadenylation element-binding protein 4 that is encoded in the genome of human.
Short Label hCPEB4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q17RY0 (CPEB4) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
R23 Methylation PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
S97 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 24275569
S99 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S137 Phosphorylation PhosphoSitePlus   UniProt 24275569
R251 Methylation PhosphoSitePlus
S252 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S255 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
T326 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S330 Phosphorylation PhosphoSitePlus   UniProt 20068231
S332 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
K336 Ubiquitination PhosphoSitePlus
S340 Phosphorylation PhosphoSitePlus
K347 Ubiquitination PhosphoSitePlus
T380 Phosphorylation PhosphoSitePlus
K505 Acetylation PhosphoSitePlus
K509 Acetylation PhosphoSitePlus
K554 Ubiquitination PhosphoSitePlus
Y604 Phosphorylation PhosphoSitePlus
Y609 Phosphorylation PhosphoSitePlus
T614 Phosphorylation PhosphoSitePlus
Y620 Phosphorylation PhosphoSitePlus
Y635 Phosphorylation PhosphoSitePlus
S725 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S97 Phosphorylation HPRD 18669648, 20068231
S99 Phosphorylation HPRD 19413330, 20068231
S252 Phosphorylation HPRD 18669648, 20068231
S255 Phosphorylation HPRD 18669648, 20068231
T326 Phosphorylation HPRD 18669648
S330 Phosphorylation HPRD 20068231
S332 Phosphorylation HPRD 18669648, 20068231
T380 Phosphorylation HPRD 18452278

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S99 N99 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
T326 M326 Biomuta DOID:1115 / sarcoma [ tcga ]
S332 L332 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]
K509 R509 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
K554 N554 Biomuta DOID:3571 / liver cancer [ icgc ]
Y609 C609 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]