iPTMnet Report for Q16881 (TXNRD1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16881 / TRXR1_HUMAN
Protein Name Thioredoxin reductase 1, cytoplasmic
Gene Name Name: TXNRD1
Synonyms:GRIM12,KDRF;
Organism Homo sapiens (Human)

PRO ID PR:Q16881
DAG View
PRO Name thioredoxin reductase 1, cytoplasmic (human)
Definition A thioredoxin reductase 1, cytoplasmic that is encoded in the genome of human.
Short Label hTXNRD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16881 (TXNRD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 22223895
T39 Phosphorylation PhosphoSitePlus
T50 Phosphorylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
K138 Methylation PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
K150 Methylation PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus
Y161 Phosphorylation PhosphoSitePlus
Y163 Phosphorylation PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
Y184 Phosphorylation PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
T195 Phosphorylation PhosphoSitePlus
T197 Phosphorylation PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
K218 Acetylation PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
K239 Acetylation PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
K245 Acetylation PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
Y277 Phosphorylation PhosphoSitePlus
Y281 Phosphorylation PhosphoSitePlus   UniProt 15592455
R289 Methylation PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
K298 Acetylation PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus
Y302 Phosphorylation PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
C339 Methylation IEDB 31844290
K385 Ubiquitination PhosphoSitePlus
K396 Ubiquitination PhosphoSitePlus
K405 Acetylation PhosphoSitePlus
K405 Sumoylation PhosphoSitePlus
K405 Ubiquitination PhosphoSitePlus
T413 Phosphorylation PhosphoSitePlus
Y434 Phosphorylation PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
K458 Ubiquitination PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus
K465 Ubiquitination PhosphoSitePlus
T469 Phosphorylation PhosphoSitePlus
T474 Phosphorylation PhosphoSitePlus
Y478 Phosphorylation PhosphoSitePlus
K489 Ubiquitination PhosphoSitePlus
T493 Phosphorylation PhosphoSitePlus
K514 Ubiquitination PhosphoSitePlus
K539 Ubiquitination PhosphoSitePlus
Y555 Phosphorylation PhosphoSitePlus
Y572 Phosphorylation PhosphoSitePlus
K574 Ubiquitination PhosphoSitePlus
K580 Ubiquitination PhosphoSitePlus
K607 Ubiquitination PhosphoSitePlus
K613 Ubiquitination PhosphoSitePlus
C647 S-Nitrosylation dbSNO 26338901
Site PTM Type PTM Enzyme Score Source PMID
S160 Phosphorylation HPRD 20068231
Y161 Phosphorylation HPRD 15592455, 20068231
Y163 Phosphorylation HPRD 15592455, 20068231
T201 Phosphorylation HPRD 20068231
Y281 Phosphorylation HPRD 15592455, 18083107
Y572 Phosphorylation HPRD 15592455
Site PTM Type PTM Enzyme Score Source PMID
S30 Phosphorylation PhosphoSitePlus
S31 Phosphorylation PhosphoSitePlus
Y251 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
S62 Phosphorylation HPRD 20068231
Y63 Phosphorylation HPRD 15592455, 20068231
Y65 Phosphorylation HPRD 15592455, 20068231
T103 Phosphorylation HPRD 20068231
Y183 Phosphorylation HPRD 15592455, 18083107
Y474 Phosphorylation HPRD 15592455
Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation HPRD 20068231
Y11 Phosphorylation HPRD 15592455, 20068231
Y13 Phosphorylation HPRD 15592455, 20068231
T51 Phosphorylation HPRD 20068231
Y131 Phosphorylation HPRD 15592455, 18083107
Y422 Phosphorylation HPRD 15592455