iPTMnet Report for Q16880 (UGT8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16880 / CGT_HUMAN
Protein Name 2-hydroxyacylsphingosine 1-beta-galactosyltransferase precursor
Gene Name Name: UGT8
Synonyms:CGT,UGT4;
Organism Homo sapiens (Human)

PRO ID PR:Q16880
DAG View
PRO Name 2-hydroxyacylsphingosine 1-beta-galactosyltransferase (human)
Definition A 2-hydroxyacylsphingosine 1-beta-galactosyltransferase that is encoded in the genome of human.
Short Label hUGT8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16880 (UGT8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N78 N-Glycosylation GlyGen 29741879, 24190977
S79 O-Glycosylation GlyGen 34846842, 34019948, 35254053
S82 O-Glycosylation GlyGen 34846842
K128 Ubiquitination PhosphoSitePlus
Y299 Phosphorylation PhosphoSitePlus
S301 Phosphorylation PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus
N333 N-Glycosylation GlyGen 29741879
K407 Ubiquitination PhosphoSitePlus
K428 Ubiquitination PhosphoSitePlus
N442 N-Glycosylation GlyGen 29741879, 24190977
T444 Phosphorylation PhosphoSitePlus
Y519 Phosphorylation PhosphoSitePlus
Y528 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N78 K78 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S301 T301 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y528 H528 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]