Protein Information

Cytoscape View

UniProt AC / UniProt ID Q16854 / DGUOK_HUMAN
Protein Name Deoxyguanosine kinase, mitochondrial precursor
Gene Name Name: DGUOK
Organism Homo sapiens (Human)

PRO ID PR:Q16854
DAG View
PRO Name deoxyguanosine kinase, mitochondrial (human)
Definition A deoxyguanosine kinase, mitochondrial that is encoded in the genome of human.
Short Label hDGUOK
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q16854 (DGUOK) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S42 Phosphorylation PhosphoSitePlus
K56 Acetylation PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
K275 Acetylation PhosphoSitePlus   UniProt 19608861
K275 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S42 F42 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
K60 R60 Biomuta DOID:263 / kidney cancer [ cosmic ]
K275 N275 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:0070003 / blastoma [ cosmic ]