iPTMnet Report for Q16854 (DGUOK)
Protein Information
| UniProt AC / UniProt ID | Q16854 / DGUOK_HUMAN |
| Protein Name | Deoxyguanosine kinase, mitochondrial precursor |
| Gene Name | Name: DGUOK Synonyms:DGK; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q16854 |
| PRO Name | deoxyguanosine kinase, mitochondrial (human) |
| Definition | A deoxyguanosine kinase, mitochondrial that is encoded in the genome of human. |
| Short Label | hDGUOK |
| Category | organism-gene |
DAG ViewQ16854 (DGUOK) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S42 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K56 | Acetylation | score1 | PhosphoSitePlus | |||
| K60 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K120 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K129 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C199 | Methylation | score1 | IEDB | 31844290 | ||
| K275 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K275 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S42 | F42 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| K60 | R60 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| K275 | N275 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ] |
