Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16829 / DUS7_HUMAN
Protein Name Dual specificity protein phosphatase 7
Gene Name Name: DUSP7
Synonyms:PYST2;
Organism Homo sapiens (Human)

PRO ID PR:Q16829
DAG View
PRO Name dual specificity protein phosphatase 7 (human)
Definition A dual specificity protein phosphatase 7 that is encoded in the genome of human.
Short Label hDUSP7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16829 (DUSP7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K2 Methylation PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
T132 Phosphorylation PhosphoSitePlus
Y136 Phosphorylation PhosphoSitePlus
T140 Phosphorylation PhosphoSitePlus
S152 Phosphorylation PhosphoSitePlus
Y169 Phosphorylation PhosphoSitePlus
Y170 Phosphorylation PhosphoSitePlus
K268 Ubiquitination PhosphoSitePlus
S315 Phosphorylation phospho.ELM 18220336
K362 Ubiquitination PhosphoSitePlus
K365 Ubiquitination PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
S369 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S366 Phosphorylation HPRD 20166139


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S152 C152 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
K365 T365 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
S366 A366 Biomuta DOID:3070 / malignant glioma [ cosmic ]
S366 C366 Biomuta DOID:3070 / malignant glioma [ cosmic ]