Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16827 / PTPRO_HUMAN
Protein Name Receptor-type tyrosine-protein phosphatase O precursor
Gene Name Name: PTPRO
Synonyms:GLEPP1,PTPU2;
Organism Homo sapiens (Human)

PRO ID PR:Q16827
DAG View
PRO Name receptor-type tyrosine-protein phosphatase O (human)
Definition A receptor-type tyrosine-protein phosphatase O that is encoded in the genome of human.
Short Label hPTPRO
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16827 (PTPRO) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T840 Phosphorylation PhosphoSitePlus
S865 Phosphorylation PhosphoSitePlus
K928 Ubiquitination PhosphoSitePlus
T1181 Phosphorylation PhosphoSitePlus
Y1185 Phosphorylation PhosphoSitePlus
S1206 Phosphorylation PhosphoSitePlus
Y1210 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S877 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T840 I840 Biomuta DOID:3371 / chondrosarcoma [ cosmic ]
S865 F865 Biomuta DOID:1909 / melanoma [ tcga ]
K928 R928 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:10283 / prostate cancer [ cosmic ]
S1206 G1206 Biomuta DOID:363 / uterine cancer [ cosmic, tcga ]