iPTMnet Report for Q16827 (PTPRO)
Protein Information
| UniProt AC / UniProt ID | Q16827 / PTPRO_HUMAN |
| Protein Name | Receptor-type tyrosine-protein phosphatase O precursor |
| Gene Name | Name: PTPRO Synonyms:GLEPP1,PTPU2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q16827 |
| PRO Name | receptor-type tyrosine-protein phosphatase O (human) |
| Definition | A receptor-type tyrosine-protein phosphatase O that is encoded in the genome of human. |
| Short Label | hPTPRO |
| Category | organism-gene |
DAG ViewQ16827 (PTPRO) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S156 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
| T840 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S865 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K928 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y1007 | Phosphorylation | score0 | RLIMS-P | 30783489 | ||
| T1181 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1185 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1206 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1210 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S877 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T840 | I840 | Biomuta | DOID:184 / bone cancer [ cosmic ] | |
| S865 | F865 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| K928 | R928 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
| S1206 | G1206 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
