iPTMnet Report for Q16821 (PPP1R3A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16821 / PPR3A_HUMAN
Protein Name Protein phosphatase 1 regulatory subunit 3A
Gene Name Name: PPP1R3A
Synonyms:PP1G;
Organism Homo sapiens (Human)

PRO ID PR:Q16821
DAG View
PRO Name protein phosphatase 1 regulatory subunit 3A (human)
Definition A protein phosphatase 1 regulatory subunit 3A that is encoded in the genome of human.
Short Label hPPP1R3A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16821 (PPP1R3A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S46 Phosphorylation P51812 (RPS6KA3) PhosphoSitePlus 10748124
S48 Phosphorylation phospho.ELM   PhosphoSitePlus 2152882, 10648825
S49 Phosphorylation PhosphoSitePlus
S65 Phosphorylation P51812 (RPS6KA3) phospho.ELM   PhosphoSitePlus 10748124, 2152882, 10648825
S332 Phosphorylation PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus
T735 Phosphorylation PhosphoSitePlus
T736 Phosphorylation PhosphoSitePlus
S739 Phosphorylation PhosphoSitePlus
T759 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
T822 Phosphorylation PhosphoSitePlus
S824 Phosphorylation PhosphoSitePlus
Y826 Phosphorylation PhosphoSitePlus
T939 Phosphorylation PhosphoSitePlus
T940 Phosphorylation PhosphoSitePlus
S1066 Phosphorylation PhosphoSitePlus
S1069 Phosphorylation PhosphoSitePlus
Y1101 Phosphorylation IEDB 35494241
Site PTM Type PTM Enzyme Score Source PMID
S46 Phosphorylation Q15418 (RPS6KA1) HPRD 10648825
S65 Phosphorylation HPRD 106488285
T759 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S48 F48 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S48 C48 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S65 L65 Biomuta DOID:4159 / skin cancer [ cosmic ]
S375 Y375 Biomuta DOID:1319 / brain cancer [ icgc ]
S375 F375 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T735 A735 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S739 N739 Biomuta DOID:184 / bone cancer [ cosmic ]
T822 I822 Biomuta DOID:4159 / skin cancer [ cosmic ]
S824 C824 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S824 P824 Biomuta DOID:1319 / brain cancer [ cosmic ]
T939 S939 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S1066 Y1066 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1069 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y1101 C1101 Biomuta DOID:1324 / lung cancer [ cosmic ]