iPTMnet Report for Q16799 (RTN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16799 / RTN1_HUMAN
Protein Name Reticulon-1
Gene Name Name: RTN1
Synonyms:NSP;
Organism Homo sapiens (Human)

PRO ID PR:Q16799
DAG View
PRO Name reticulon-1 (human)
Definition A reticulon-1 that is encoded in the genome of human.
Short Label hRTN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16799 (RTN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T34 Phosphorylation PhosphoSitePlus
S48 Phosphorylation PhosphoSitePlus
S65 Phosphorylation PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus
S139 Phosphorylation PhosphoSitePlus
T145 Phosphorylation PhosphoSitePlus
S166 Phosphorylation PhosphoSitePlus
T200 O-Glycosylation GlyGen 28657654
T278 Phosphorylation PhosphoSitePlus
T279 Phosphorylation PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus
T300 Phosphorylation PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus
S352 Phosphorylation phospho.ELM   PhosphoSitePlus 18088087
Y368 Phosphorylation PhosphoSitePlus
S487 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18088087, 24275569
K650 Ubiquitination PhosphoSitePlus
T651 Phosphorylation PhosphoSitePlus
K772 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S48 Phosphorylation HPRD 19415658
S352 Phosphorylation HPRD 18088087, 19664994, 19415658, ...20058876, 18707149
S487 Phosphorylation HPRD 18088087
Site PTM Type PTM Enzyme Score Source PMID
S15 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S48 R48 Biomuta DOID:4159 / skin cancer [ cosmic ]
T200 P200 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T279 P279 Biomuta DOID:1612 / breast cancer [ cosmic ]
S291 F291 Biomuta DOID:4159 / skin cancer [ cosmic ]
T300 I300 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S487 T487 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K650 N650 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]