iPTMnet Report for Q16798 (ME3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16798 / MAON_HUMAN
Protein Name NADP-dependent malic enzyme, mitochondrial precursor
Gene Name Name: ME3
Organism Homo sapiens (Human)

PRO ID PR:Q16798
DAG View
PRO Name NADP-dependent malic enzyme, mitochondrial (human)
Definition An NADP-dependent malic enzyme, mitochondrial that is encoded in the genome of human.
Short Label hME3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16798 (ME3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T7 Phosphorylation PhosphoSitePlus
T9 Phosphorylation PhosphoSitePlus
Y107 Phosphorylation PhosphoSitePlus
T112 Phosphorylation PhosphoSitePlus
K119 Acetylation PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
S467 Phosphorylation PhosphoSitePlus
S469 Phosphorylation PhosphoSitePlus
T540 Phosphorylation PhosphoSitePlus
S545 Phosphorylation PhosphoSitePlus
Y555 Phosphorylation PhosphoSitePlus
T581 Phosphorylation PhosphoSitePlus
S591 Phosphorylation PhosphoSitePlus
Y592 Phosphorylation PhosphoSitePlus
T593 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y107 C107 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1319 / brain cancer [ icgc ]
S545 Y545 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S545 F545 Biomuta DOID:9256 / colorectal cancer [ cosmic ]