iPTMnet Report for Q16774 (GUK1)
Protein Information
| UniProt AC / UniProt ID | Q16774 / KGUA_HUMAN |
| Protein Name | Guanylate kinase |
| Gene Name | Name: GUK1 Synonyms:GMK,GMPK; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q16774 |
| PRO Name | guanylate kinase (human) |
| Definition | A guanylate kinase that is encoded in the genome of human. |
| Short Label | hGUK1 |
| Category | organism-gene |
DAG ViewQ16774 (GUK1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S2 | Acetylation | score1 | UniProt | 19413330 | ||
| S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K17 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K51 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y53 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y54 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K111 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K147 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S158 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S159 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S173 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y178 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S2 | L2 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| Y54 | C54 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
