iPTMnet Report Q16773 KYAT1

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q16773 / KAT1_HUMAN
Protein Name	Kynurenine--oxoglutarate transaminase 1
Gene Name	Name: KYAT1 Synonyms:CCBL1;
Organism	Homo sapiens (Human)

PRO ID	PR:Q16773 DAG View
PRO Name	kynurenine--oxoglutarate transaminase 1 (human)
Definition	A kynurenine--oxoglutarate transaminase 1 that is encoded in the genome of human.
Short Label	hKYAT1
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q16773 (KYAT1) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	K3	Ubiquitination		score1	PhosphoSitePlus
	Y15	Phosphorylation		score1	PhosphoSitePlus
	T172	Phosphorylation		score1	PhosphoSitePlus
	K176	Ubiquitination		score1	PhosphoSitePlus
	T182	Phosphorylation		score1	PhosphoSitePlus
	K247	Ubiquitination		score1	PhosphoSitePlus
	K414	Ubiquitination		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T172	Phosphorylation		score0	HPRD	20068231
	T175	Phosphorylation		score0	HPRD	20068231
	T182	Phosphorylation		score0	HPRD	20068231

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
K3	E3	Biomuta		DOID:3571 / liver cancer [ cosmic ]
Y15	C15	Biomuta		DOID:9256 / colorectal cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ]
K247	N247	Biomuta		DOID:363 / uterine cancer [ cosmic, icgc ]