Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16769 / QPCT_HUMAN
Protein Name Glutaminyl-peptide cyclotransferase precursor
Gene Name Name: QPCT
Organism Homo sapiens (Human)

PRO ID PR:Q16769
DAG View
PRO Name glutaminyl-peptide cyclotransferase (human)
Definition A glutaminyl-peptide cyclotransferase that is encoded in the genome of human.
Short Label hQPCT
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16769 (QPCT) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N49 N-Glycosylation GlyGen   UniProt 21671571, 23090970, 14680951, ...24190977
S119 Phosphorylation PhosphoSitePlus
T126 Phosphorylation PhosphoSitePlus
T130 Phosphorylation PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
N296 N-Glycosylation GlyGen 23090970, 24190977
T343 Phosphorylation IEDB 35494241


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S119 Y119 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S119 F119 Biomuta DOID:4159 / skin cancer [ cosmic ]
K132 T132 Biomuta DOID:4606 / bile duct cancer [ cosmic ]