iPTMnet Report for Q16763 (UBE2S)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16763 / UBE2S_HUMAN
Protein Name Ubiquitin-conjugating enzyme E2 S
Gene Name Name: UBE2S
Synonyms:E2EPF;ORFNames:OK/SW-cl.73;
Organism Homo sapiens (Human)

PRO ID PR:Q16763
DAG View
PRO Name ubiquitin-conjugating enzyme E2 S (human)
Definition A ubiquitin-conjugating enzyme E2 S that is encoded in the genome of human.
Short Label hUBE2S
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16763 (UBE2S) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
K18 Ubiquitination PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
K68 Acetylation PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
S73 Phosphorylation HPRD   PhosphoSitePlus 20068231
K76 Ubiquitination PhosphoSitePlus
Y78 Phosphorylation PhosphoSitePlus
T81 Phosphorylation PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
T152 Phosphorylation P31749 (AKT1) PhosphoSitePlus   RLIMS-P+   Signor 27593939
S173 Phosphorylation PhosphoSitePlus   UniProt 23186163
T175 Phosphorylation HPRD   phospho.ELM 18669648
T180 Phosphorylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K100 N100 Biomuta DOID:1324 / lung cancer [ cosmic ]
T180 S180 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]