iPTMnet Report for Q16760 (DGKD)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16760 / DGKD_HUMAN
Protein Name Diacylglycerol kinase delta
Gene Name Name: DGKD
Synonyms:KIAA0145;
Organism Homo sapiens (Human)

PRO ID PR:Q16760
DAG View
PRO Name diacylglycerol kinase delta (human)
Definition A diacylglycerol kinase delta that is encoded in the genome of human.
Short Label hDGKD
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16760 (DGKD) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S44 Phosphorylation PhosphoSitePlus
T45 Phosphorylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
S66 Phosphorylation phospho.ELM   PhosphoSitePlus 15228384
S70 Phosphorylation phospho.ELM   PhosphoSitePlus 15228384
T81 O-Glycosylation GlyGen 30379171, 35254053
T87 O-Glycosylation GlyGen 30379171, 35254053
K89 Ubiquitination PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
K434 Ubiquitination PhosphoSitePlus
T440 Phosphorylation PhosphoSitePlus
K454 Ubiquitination PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
K512 Ubiquitination PhosphoSitePlus
K524 Ubiquitination PhosphoSitePlus
K545 Ubiquitination PhosphoSitePlus
S615 Phosphorylation PhosphoSitePlus
S668 Phosphorylation PhosphoSitePlus
S681 O-Glycosylation GlyGen 30379171, 35254053
K687 Ubiquitination PhosphoSitePlus
K691 Ubiquitination PhosphoSitePlus
K718 Ubiquitination PhosphoSitePlus
Y757 Phosphorylation PhosphoSitePlus
K783 Ubiquitination PhosphoSitePlus
K815 Ubiquitination PhosphoSitePlus
K950 Ubiquitination PhosphoSitePlus
S1057 Phosphorylation PhosphoSitePlus
K1185 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S66 Phosphorylation HPRD 15228384
S66 Phosphorylation P17252 (PRKCA) HPRD 15228384
S70 Phosphorylation HPRD 15228384
S70 Phosphorylation P17252 (PRKCA) HPRD 15228384
Site PTM Type PTM Enzyme Score Source PMID
Y6 Phosphorylation PhosphoSitePlus
S22 Phosphorylation HPRD 15228384
S22 Phosphorylation P17252 (PRKCA) HPRD 15228384
S26 Phosphorylation HPRD 15228384
S26 Phosphorylation P17252 (PRKCA) HPRD 15228384


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S22 A22 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S66 A66 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
T81 M81 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K123 T123 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K337 N337 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T440 A440 Biomuta DOID:1319 / brain cancer [ cosmic ]
S460 F460 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K512 N512 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
K687 N687 Biomuta DOID:363 / uterine cancer [ icgc ]