iPTMnet Report for Q16656 (NRF1)
Protein Information
UniProt AC / UniProt ID | Q16656 / NRF1_HUMAN |
Protein Name | Nuclear respiratory factor 1 |
Gene Name | Name: NRF1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q16656 |
PRO Name | nuclear respiratory factor 1 (human) |
Definition | A nuclear respiratory factor 1 that is encoded in the genome of human. |
Short Label | hNRF1 |
Category | organism-gene |
Q16656 (NRF1) as Substrate
Site | PTM Type | PTM Enzyme |
Score
| Source | PMID | |
---|---|---|---|---|---|---|
S39 | Phosphorylation | score2 | UniProt | 9228045 | ||
S44 | Phosphorylation | score2 | UniProt | 9228045 | ||
S46 | Phosphorylation | score2 | UniProt | 9228045 | ||
S47 | Phosphorylation | score4 | RLIMS-P UniProt | 16864783, 9228045 | ||
S52 | Phosphorylation | score2 | UniProt | 9228045 | ||
T87 | Phosphorylation | score1 | PhosphoSitePlus | |||
K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
S99 | Phosphorylation | score1 | PhosphoSitePlus | |||
S102 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 31350280 | ||
T109 | Phosphorylation | score0 | RLIMS-P | 25965299 | ||
T118 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y122 | Phosphorylation | score1 | PhosphoSitePlus | |||
T123 | Phosphorylation | score1 | PhosphoSitePlus | |||
S136 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 31350280 | ||
S138 | Phosphorylation | score1 | PhosphoSitePlus | |||
K139 | Ubiquitination | score1 | PhosphoSitePlus | |||
K214 | Ubiquitination | score1 | PhosphoSitePlus | |||
K221 | Acetylation | score1 | PhosphoSitePlus | |||
K226 | Acetylation | score1 | PhosphoSitePlus | |||
K230 | Ubiquitination | score1 | PhosphoSitePlus | |||
T259 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 30642892 | ||
K267 | Ubiquitination | score1 | PhosphoSitePlus | |||
T294 | O-Glycosylation | score1 | GlyGen | 23301498, 33214551, 35138101, ...34725712, 29351928, 34019948, 29485866, 32119511 | ||
S296 | O-Glycosylation | score1 | GlyGen | 23301498, 33214551, 35138101, ...34725712, 29351928, 34019948, 29485866, 32119511 | ||
S303 | O-Glycosylation | score1 | GlyGen | 23301498, 33214551, 35138101, ...34725712, 29351928, 34019948, 29485866, 32119511 | ||
T369 | O-Glycosylation | score1 | GlyGen | 23301498, 33214551, 35138101, ...34725712, 29351928, 34019948, 29485866, 32119511 | ||
S432 | O-Glycosylation | score1 | GlyGen | 23301498, 33214551, 35138101, ...34725712, 29351928, 34019948, 29485866, 32119511 | ||
T443 | O-Glycosylation | score1 | GlyGen | 23301498, 33214551, 35138101, ...34725712, 29351928, 34019948, 29485866, 32119511 | ||
S457 | O-Glycosylation | score1 | GlyGen | 23301498, 33214551, 35138101, ...34725712, 29351928, 34019948, 29485866, 32119511 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S44 | L44 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic ] | |
S46 | F46 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S47 | L47 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S102 | F102 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T109 | A109 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
T118 | M118 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
T123 | S123 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K230 | M230 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K230 | N230 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S303 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T369 | I369 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S432 | F432 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |