iPTMnet Report for Q16650 (TBR1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16650 / TBR1_HUMAN
Protein Name T-box brain protein 1
Gene Name Name: TBR1
Organism Homo sapiens (Human)

PRO ID PR:Q16650
DAG View
PRO Name T-box brain protein 1 (human)
Definition A T-box brain protein 1 that is encoded in the genome of human.
Short Label hTBR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16650 (TBR1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S74 Phosphorylation PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
S84 Phosphorylation PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
T408 Phosphorylation PhosphoSitePlus
S410 Phosphorylation PhosphoSitePlus
Y425 Phosphorylation PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus
Y440 Phosphorylation PhosphoSitePlus
S480 Phosphorylation PhosphoSitePlus
S549 Phosphorylation PhosphoSitePlus
S594 Phosphorylation PhosphoSitePlus
S610 Phosphorylation PhosphoSitePlus
S613 Phosphorylation PhosphoSitePlus
S623 Phosphorylation PhosphoSitePlus
S629 Phosphorylation PhosphoSitePlus
Y632 Phosphorylation PhosphoSitePlus
S641 Phosphorylation PhosphoSitePlus
S648 O-Glycosylation GlyGen 30379171, 28657654
S652 Phosphorylation PhosphoSitePlus
S656 Phosphorylation PhosphoSitePlus
K666 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S91 Y91 Biomuta DOID:1319 / brain cancer [ icgc ]
K228 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S430 C430 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S594 L594 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S656 T656 Biomuta DOID:184 / bone cancer [ cosmic ]