iPTMnet Report for Q16649 (NFIL3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16649 / NFIL3_HUMAN
Protein Name Nuclear factor interleukin-3-regulated protein
Gene Name Name: NFIL3
Synonyms:E4BP4,IL3BP1;
Organism Homo sapiens (Human)

PRO ID PR:Q16649
DAG View
PRO Name nuclear factor interleukin-3-regulated protein (human)
Definition A nuclear factor interleukin-3-regulated protein that is encoded in the genome of human.
Short Label hNFIL3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16649 (NFIL3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S30 Phosphorylation PhosphoSitePlus
K72 Sumoylation PhosphoSitePlus
K82 Acetylation PhosphoSitePlus
K82 Sumoylation PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
K219 Sumoylation PhosphoSitePlus
S258 Phosphorylation PhosphoSitePlus
S275 Phosphorylation HPRD   PhosphoSitePlus 18452278
S285 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S286 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231, 18452278
S301 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 19651622, ...18669648, 20068231
K306 Sumoylation PhosphoSitePlus
K337 Sumoylation PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
S352 Phosphorylation HPRD   PhosphoSitePlus 20068231
S353 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 19691289, 20068231
K360 Ubiquitination PhosphoSitePlus
K394 Sumoylation PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
K406 Sumoylation PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
K412 Sumoylation PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
K419 Sumoylation PhosphoSitePlus
K419 Ubiquitination PhosphoSitePlus
K424 Sumoylation PhosphoSitePlus
K424 Ubiquitination PhosphoSitePlus
K434 Ubiquitination PhosphoSitePlus
S446 Phosphorylation PhosphoSitePlus
K448 Ubiquitination PhosphoSitePlus
S459 Phosphorylation PhosphoSitePlus
S461 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S30 Y30 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K82 E82 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K116 N116 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S275 L275 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S352 F352 Biomuta DOID:4159 / skin cancer [ cosmic ]
S461 Y461 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]