iPTMnet Report Q16611 BAK1

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q16611 / BAK_HUMAN
Protein Name	Bcl-2 homologous antagonist/killer
Gene Name	Name: BAK1 Synonyms:BAK,BCL2L7,CDN1;
Organism	Homo sapiens (Human)

PRO ID	PR:Q16611 DAG View
PRO Name	Bcl-2 homologous antagonist/killer (human)
Definition	A Bcl-2 homologous antagonist/killer that is encoded in the genome of human.
Short Label	hBAK1
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q16611 (BAK1) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	A2	Acetylation		score1	UniProt	19413330, 25944712
	S91	Phosphorylation		score0	RLIMS-P	23189150
	Y108	Phosphorylation	P51813 (BMX)	score4	PhosphoSitePlus RLIMS-P	20959805, 23303126, 25649765
	Y110	Phosphorylation		score3	PhosphoSitePlus RLIMS-P	23782464
	K113	Ubiquitination		score1	PhosphoSitePlus
	S117	Phosphorylation		score3	PhosphoSitePlus RLIMS-P	23189150
	T148	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	M1	Acetylation		score1	PRO

Proteoforms

	PRO ID (Short Label)	Sites	PTM Enzyme	Source	PMID
	PR:000036224 (hBAK1/Ac:1)	acM1		PRO

Proteoform PPIs

	Protein 1	Relation	Protein 2	Source	PMID
	PR:Q07817-1 (hBCL2L1/iso:1)	Interaction	PR:Q16611 (hBAK1)	PRO	8596636

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
Y110	H110	Biomuta		DOID:10534 / stomach cancer [ cosmic, icgc ]