iPTMnet Report for Q16610 (ECM1)
Protein Information
| UniProt AC / UniProt ID | Q16610 / ECM1_HUMAN |
| Protein Name | Extracellular matrix protein 1 precursor |
| Gene Name | Name: ECM1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q16610 |
| PRO Name | extracellular matrix protein 1 (human) |
| Definition | An extracellular matrix protein 1 that is encoded in the genome of human. |
| Short Label | hECM1 |
| Category | organism-gene |
DAG ViewQ16610 (ECM1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T3 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S18 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T26 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| T28 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| Y43 | O-Glycosylation | score3 | GlyGen | 23584533, 23399548, 25813380 | ||
| Y43 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S48 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
| S52 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| S63 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S80 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T84 | O-Glycosylation | score1 | GlyGen | 30459171, 25813380 | ||
| S119 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
| T130 | O-Glycosylation | score1 | GlyGen | 30459171, 25813380 | ||
| S138 | O-Glycosylation | score1 | GlyGen | 30459171, 25813380 | ||
| N311 | N-Glycosylation | score1 | GlyGen | 29391424 | ||
| N353 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| N354 | N-Glycosylation | score1 | GlyGen | 29741879, 29391424, 24190977 | ||
| T391 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| T411 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T418 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T433 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N444 | N-Glycosylation | score2 | GlyGen UniProt | 16335952, 29741879, 19139490, ... | ||
| N530 | N-Glycosylation | score1 | GlyGen | 29741879, 26791533, 29391424 | ||
| T534 | O-Glycosylation | score1 | GlyGen | 25813380, 30237853 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S48 | F48 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S63 | F63 | Biomuta | [ cosmic ] | |
| T84 | I84 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T130 | M130 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic, icgc ] | |
| N311 | Y311 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| N530 | H530 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| T534 | N534 | Biomuta | DOID:2998 / testicular cancer [ cosmic ] |
